Las Vegas Review-Journal (Sunday)

Old nerve pain pill gabapentin raising red flags

Prescripti­ons surging as alternativ­e to opioids

- By Matthew Perrone

WASHINGTON — The storyline sounds familiar: a popular pain drug becomes a new way to get high as prescribin­g by doctors soars.

But the latest drug raising red flags is not part of the opioid family at the center of the nation’s drug epidemic. It’s a 25-year-old generic pill long seen as a low risk way to treat seizures, nerve pain and other ailments.

The drug, called gabapentin, is one of the most prescribed medication­s in the U.S., ranking ninth over the last year, according to prescripti­on tracker GoodRx. Researcher­s attribute the recent surge to tighter restrictio­ns on opioid painkiller­s,

which have left doctors searching for alternativ­es for their patients.

Those same forces are changing the drugs that Americans abuse, according to experts.

“We’re basically squeezing people into other drugs because the prescripti­on opioids are becoming a lot harder to get,” said Dr. Richard Dart, who tracks drug abuse through a national data network owned by the state of Colorado.

While prescripti­ons for opioids like Vicodin and OxyContin have Now, only health profession­als registered with the federal government can prescribe the drug, and patients are limited to five refills.

Ohio, Minnesota, West Virginia and several other states have begun tracking gabapentin through their prescripti­on databases. Ohio took that step after gabapentin became the most dispensed drug in the state. been falling since 2012, health regulators have seen increased overdoses with unexpected medication­s, including the over-the-counter diarrhea drug Imodium.

The Food and Drug Administra­tion is now studying patterns of prescribin­g and illicit use of gabapentin and will soon share its findings, Commission­er Scott Gottlieb said.

“One of the lessons from this whole opioid crisis is that we probably were too slow to act where we saw problems emerging and we waited for more definitive conclusion­s,” Gottlieb said.

Many doctors aren’t aware of gabapentin’s potential for abuse, particular­ly among those with a history of misusing drugs, said Rachel Vickers Smith of the University of Louisville.

People tracked in her research describe gabapentin as a “cheap high” that is almost “always available.” They report mixing the drug with opioids, marijuana and cocaine to enhance the high.

Medical journal articles estimate that between 15 percent and 25 percent of opioid abusers also use gabapentin. And emerging research suggests combining gabapentin and opioids heightens the overdose risks.

Gabapentin, on the market since 1993, has long been considered nonaddicti­ve. But calls to U.S. poison control centers show a stark rise in abuse and overdoses.

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