ATLANTIC COAST CONFERENCE

■ No. 2 Clemson 59, Florida State 10 — At Tallahassee, Fla., Trevor Lawrence threw for 314 yards and four touchdowns, two each to Tee Higgins and Amari Rodgers, as the Tigers (8-0, 5-0) dealt the Seminoles (4-4, 2-4) their most decisive home loss and won a fourth straight for the first time in a series that dates to 1970.

■ Syracuse 51, No. 22 North Carolina State 41 — At Syracuse, N.Y., Eric Dungey threw for 411 yards and three touchdowns and ran for a score for the Orange (6-2, 3-2). Ryan Finley threw for 473 yards and three TDs, two to Kelvin Harmon, who totaled 11 catches for 247 yards receiving for the Wolfpack (5-2, 2-2).

■ Wake Forest 56, Louisville 35

— At Louisville, Ky., Matt Colburn II, who verbally had committed to the Cardinals (2-6, 0-5) before they pulled his scholarship offer, ran for 243 yards and three touchdowns on 20 carries for the Demon Deacons (4-4, 1-3). Trey Smith ran for 98 yards and three TDs for Louisville, which was outgained 591-532 in yards of offense.

■ Virginia 31, North Carolina 21 — At Charlottesville, Va., Bryce Perkins threw for three touchdowns and ran for 112 yards and a TD for the Cavaliers (6-2, 4-1), who dealt the Tar Heels (1-6, 1-4) their fourth straight loss. North Carolina mustered 66 yards rushing.

■ Pittsburgh 54, Duke 45 — At Pittsburgh, Maurice Ffrench caught the decisive touchdown pass with five seconds left and had a 50-yard TD reception in the second quarter for the Panthers (4-4, 3-1). Deon Jackson set a program record for the Blue Devils (5-3, 1-3) with 403 all-purpose yards.