Washington (1-0) at Cardinals (1-0)

Giants (0-1) at Bears (1-0)

■ Time: 10 a.m.

■ Line/total: Bears -5 , 42

■ Analysis: The Giants lost 19-14 at Chicago last season. New York QB Daniel Jones was serviceable last week and is probably the better quarterback in this game. Jones has weapons if he can get protection from his line.

■ By the numbers: The Giants are on a 10-3 ATS run as road underdogs. … The Bears are 9-6 ATS as home favorites the last three seasons. Chicago has allowed 17 points or fewer in 11 of its last 15 games as a home favorite.

■ Pick: Bears 21, Giants 17

Jaguars (1-0) at Titans (1-0)

■ Time: 10 a.m.

■ Line/total: Titans -7 ½ , 44

■ Analysis: Jacksonville didn’t force Indianapolis to punt last week. The Jaguars took advantage of mistakes by the Colts, including two interceptions. But they lack the playmakers on defense to stop a good Titans offense.

■ By the numbers: Tennessee was 3-0 ATS as a home favorite with Ryan Tannehill starting last season against three teams that didn’t make the playoffs. … Jacksonville is on a 1-3 skid at Tennessee, with the losses by 14 points or more.

■ Pick: Titans 27, Jaguars 17

■ Time: 1:05 p.m.

■ Line/total: Cardinals -7, 46

■ Analysis: Arizona was impressive in last week’s win at San Francisco. Arguably the biggest improvement for the Cardinals was their defense, which limited the 49ers to 4.9 yards per play if you take out a screen pass that went for 75 yards. Washington sacked Carson Wentz eight times, but will struggle to do that against Arizona QB Kyler Murray and his athleticism and elusiveness. If forced to drive the length of the field, the Washington offense will struggle. But the Washington defense can hold its own and will make life tough for Arizona.

Murray averaged only 5.5 air yards per pass attempt last week, the seventh-lowest average in the league. Last season, it was the eighth lowest at 7.1 yards. That simply means Arizona uses short pass plays and long drives to score touchdowns.

Cardinals 23, Washington 17