30K in U.S. bare arms to fight virus

COVID-19 vaccine trial starts serial test barrage

The world’s biggest COVID-19 vaccine study got underway Monday with the first of 30,000 planned volunteers helping to test shots created by the U.S. government — one of several candidates in the final stretch of the global vaccine race.

There’s still no guarantee that the experimental vaccine, developed by the National Institutes of Health and Moderna Inc., will really protect.

The needed proof: Volunteers won’t know if they’re getting the real shot or a dummy version. After two doses, scientists will closely track which group experiences more infections as they go about their daily routines, especially in areas where the virus still is spreading unchecked.

“Unfortunately for the United States of America, we have plenty of infections right now” to get that answer, NIH’S Dr. Anthony Fauci said recently.

Moderna said the vaccination was done in Savannah, Georgia, the first site to get underway among more than seven dozen trial sites, including Las Vegas, scattered around the country.

In Binghamton, New York, nurse Melissa Harting said she volunteered as a way “to do my part to help out.”

“I’m excited,” Harting said before she received a study injection Monday morning. Especially with family members in front-line jobs that could expose them to the virus, “doing our part to eradicate it is very important to me.”

Several other vaccines made by China and by Britain’s Oxford University began smaller final-stage tests in Brazil and other hard-hit countries this month.

But the U.S. requires its own tests of any vaccine that might be used in the country and has set a high bar: Every month through fall, the government-funded COVID-19 Prevention Network will roll out a new study of a leading candidate — each one with 30,000 newly recruited volunteers.

The massive studies aren’t just to test if the shots work — they’re needed to check each potential vaccine’s safety. And following the same study rules will let scientists eventually compare all the shots.

It normally takes years to create a new vaccine from scratch, but scientists are setting speed records this time around, spurred by knowledge that vaccination is the world’s best hope against the pandemic.

The coronavirus wasn’t even known to exist before late December, and vaccine makers sprang into action Jan. 10 when China shared the virus’ genetic sequence.

Just 65 days later in March, the Nih-made vaccine was tested in people. The first recipient is encouraging others to volunteer now.

“We all feel so helpless right now. There’s very little that we can do to combat this virus. And being able to participate in this trial has given me a sense of, that I’m doing something,” Jennifer Haller of Seattle said. “Be prepared for a lot of questions from your friends and family about how it’s going, and a lot of thank-yous.”