Las Vegas Review-Journal

Vaccine team on to bigger numbers

Challenges remain beyond 100M shots

- By Zeke Miller

—It sounded so ambitious at first blush: 100 million vaccinatio­n shots in 100 days.

Now, one month into his presidency, Joe Biden is on a glide path to attain that goal and pitching well beyond it to the far more ambitious and daunting mission of vaccinatin­g all eligible adults against the coronaviru­s by the end of the summer.

Limited supply of the two approved COVID-19 vaccines has hampered the pace of vaccinatio­ns — and that was before extreme winter weather delayed the delivery of about 6 million doses this past week. But the

United States is on the verge of a supply breakthrou­gh as manufactur­ing ramps up and with the expectatio­n of a third vaccine becoming available in the coming weeks.

That means the act of delivering injections will soon be the dominant constraint, and it’s prompting the Biden administra­tion to push to dramatical­ly expand the universe of those who will deliver injections and where Americans will meet them to get their shots.

“It’s one thing to have the

vaccine, and it’s very different to get it in someone’s arms,” Biden said Friday as he toured Pfizer’s manufactur­ing plant in Portage, Michigan. The company is set to double its pace of vaccine deliveries in the coming weeks.

Since their approval in December, more than 75 million doses of the two-shot-regimen Moderna and Pfizer vaccines have been distribute­d, of which 63 million have been injected, reaching 13 percent of Americans. Nearly 45 million of those doses have been administer­ed since Biden’s inaugurati­on on Jan. 20.

The pace of deliveries of those vaccines is about to take off. About 145 million doses are set for delivery in the next 5 1/2 weeks, with an additional 200 million expected by the end of May and a further 200 million by the end of July.

That’s before the expected approval by the Food and Drug Administra­tion for emergency use of a third vaccine, from Johnson & Johnson. The single-dose J&J vaccine is expected to help speed the path to immunity and requires half the vaccinatio­n resources of the two-shot regimens. But there is no massive stockpile of J&J doses ready to roll out on Day One.

“We’re going to be starting with only a few million in inventory,” White House COVID-19 coordinato­r Jeff Zients said this past week. Still, when combined with the anticipate­d increases in the other vaccines, the J&J doses could prove the pivotal advance in delivering enough shots for nearly all American adults by the end of June, at least a month earlier than currently anticipate­d.

The daily inoculatio­n average climbed to 1.7 million shots per day last week, but as many as double that number of doses are soon expected to be available on average each day. The focus of Biden’s team is now quickly shifting to ensuring those doses can get used, though the administra­tion has resisted the calls of some health experts to publicly set a “moonshot” target for how many daily doses it hopes to deliver.

Biden first set his target of 100 million doses in 100 days on Dec. 8, days before the first vaccines received emergency use authorizat­ion. By Inaugurati­on Day, it was clear the U.S. was on course to attain that goal.

Dr. Leana Wen, an emergency physician and public health professor at George Washington University, said she would like to see the administra­tion commit to a more ambitious 3 million shot-per-day target.

“I want to see them put that stake in the ground and ask everyone to help them achieve that goal,” she said.

The current pace of vaccinatio­n dipped markedly in recent days as winter weather shuttered administra­tion sites in Texas and across the South, and icy conditions stranded supplies at shipping hubs in Louisville, Kentucky, and Memphis, Tennessee.

One-third of the delayed doses have already been delivered, Dr. Anthony Fauci, the nation’s top infectious disease specialist, announced Sunday. The White House expects that remaining delayed doses will be injected by March 1 and that the daily pace of vaccinatio­ns will continue to climb.

Much of the increase, according to data from the Centers for Disease Control and Prevention, comes from people receiving their second dose of the Moderna or Pfizer vaccine.

The pace of first-dose vaccinatio­ns, meanwhile, has been largely steady over the past several weeks, hovering around an average of 900,000 shots per day.

Increasing both the rate of firstdose administra­tions and the rate of overall vaccinatio­ns will be key to achieving herd immunity — estimated to require vaccinatio­n of about 80 percent of the population — in hopes of ending the pandemic and curtailing the emergence of potentiall­y even more dangerous “mutant” strains of the coronaviru­s.

That means keeping demand high. The administra­tion has expressed concerns about public surveys showing that tens of millions of Americans are reluctant to get the vaccine, and it is stepping up public outreach to overcome that hesitancy as the U.S. death toll nears 500,000 — “a terribly historic milestone in the history of this country,” as Fauci put it, and “we’re still not out of it.”

Fauci also said he expects a “significan­t degree of normality” in everyday life toward the end of the year but that it was “possible” people will still need to be wearing masks into 2022.

He says ultimately it will depend on the trajectory of COVID-19 variants as well as whether an “overwhelmi­ng majority” of people get vaccinated.

Dr. Cyrus Shahpar, the White House COVID-19 data director, said in an interview that the administra­tion is “focused on going out to communitie­s and making sure people know these vaccines are safe and how they can get them, with a goal of vaccinatin­g nearly all Americans.”

The administra­tion has also turned its focus toward identifyin­g delivery paths for the vaccines beyond those already used by states, including federally run mass vaccinatio­n sites, smaller community health centers and retail pharmacies. The White House’s goal is to stand up the sites now so that they will be ready to handle the influx of vaccine in the coming weeks.

The Pentagon, at the request of the Federal Emergency Management Agency, has started deploying thousands of active-duty troops to open mass vaccinatio­n centers across the country, with plans in place for as many as 100 sites capable of delivering 450,000 doses per day.

The administra­tion also rolled out the federal pharmacy program that had initially been announced by the Trump White House. It has delivered doses directly to chains such as CVS and Walgreens.

 ?? K.M. Cannon Las Vegas Review-journal @Kmcannonph­oto ?? Ideco Flores, an emergency medical technician with American Medical Response, vaccinates a resident Wednesday at a clinic at Chuck Minker Sports Complex.
K.M. Cannon Las Vegas Review-journal @Kmcannonph­oto Ideco Flores, an emergency medical technician with American Medical Response, vaccinates a resident Wednesday at a clinic at Chuck Minker Sports Complex.

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