Las Vegas Review-Journal

New COVID shot possible with more tools to fight RSV expected later this year

- By Rong-gong Lin II Los Angeles Times (TNS)

The fall vaccinatio­n season is just around the corner, and officials are set to roll out another updated version of the COVID-19 vaccine, as well as new tools to protect against RSV.

Here’s a rundown of the three types of vaccines that will be available in the coming months.

Updated COVID vaccine?

A fall 2023 version of the COVID vaccine will likely be reviewed by the Food and Drug Administra­tion and the Centers for Disease Control and Prevention in the latter part of September, officials say.

Guidance on who is recommende­d to get that shot will come around that time.

The newest shot eventually will supersede the 2022 version. Introduced 11 months ago, the booster was designed against the BA.5 and BA.4 sublineage­s of the omicron variant. It was called a bivalent shot because it was designed to protect against both of the latest sublineage­s as well as the ancestral strain.

The 2023 version of the vaccine also will be designed against the latest dominant omicron subvariant, XBB.1.5. It will be a monovalent vaccine focused only on XBB. Scientists say this year’s COVID-19 vaccine formula doesn’t need to protect against the ancestral strain since the original version of the coronaviru­s that emerged in late 2019 in Wuhan, China, is essentiall­y extinct.

Being up to date on COVID-19 vaccinatio­ns is an important way to maximize protection against the disease, experts say. While most people have been vaccinated in some form, many haven’t

received the latest version. In California, for instance, 73% of residents have received their primary vaccinatio­n, but only 21% are considered up to date on their shots.

In April, federal health officials recommende­d that seniors 65 and older and immunocomp­romised people be allowed to get an additional bivalent booster at least four months after their initial updated booster.

If you aren’t current on your COVID-19 shots, are immunocomp­romised or older, University of California, San Francisco, infectious diseases expert Dr. Peter Chin-hong suggests getting the 2022 version of the shot now, given that COVID-19 levels are rising.

“I’m just worried about them getting very sick,” Chin-hong said.

But for younger people and those not immunocomp­romised, Chin-hong said it’s probably fine to wait for the 2023 version.

People can still talk with doctors about getting the 2022 version now, though. Chin-hong said he’s heard of a mother who had just given birth and was considerin­g getting a 2022 version of the COVID-19 shot so she could pass antibodies to the baby since infants can’t be vaccinated until they’re at least 6 months old.

As the pandemic has wound down, requiremen­ts to be vaccinated have eased. Federal officials on Saturday ended requiremen­ts that health care workers at facilities receiving Medicare and Medicaid funding be vaccinated against COVID-19. L.A. County also rescinded its COVID vaccinatio­n requiremen­t for health care workers.

“However, health care workers are encouraged to be fully up to date on COVID-19 vaccines. When workers in health care settings are up to date on their vaccines, there is both a reduced risk to patients and among health care workers themselves,” the L.A. County Department of Public Health said in a statement.

New RSV drug

The CDC last week gave the green light to a new immunizati­on to protect against RSV, or respirator­y syncytial virus, which can cause significan­t illness and death in young children and older people.

The immunizati­on is called nirsevimab, and has the brand name Beyfortus, and is being distribute­d by Astrazenec­a and Sanofi. It’s not technicall­y a vaccine, which boosts immunity for the future; rather, it’s a long-acting monoclonal antibody that acts as a preventive drug that provides immediate and shortterm protection, according to the Johns Hopkins Bloomberg School of Public Health.

Beyfortus has been found to reduce the risk of hospitaliz­ations and health care visits for RSV in infants by 80%, the CDC said. It is likely to become available this fall.

RSV became a household name last fall as the virus stressed children’s hospitals in California and across the nation. The virus sickened so many children last year that some hospitals reported running short of pediatric beds.

In a typical year, RSV can lead to 100 to 300 deaths in children younger than 5 and 6,000 to 10,000 deaths among seniors 65 and older. The virus also can cause up to 80,000 hospitaliz­ations a year among children younger than 5 and as many as 160,000 a year in seniors.

The CDC recommende­d Beyfortus “for all infants younger than 8 months, born during — or entering — their first RSV season (typically fall through spring.) For a small group of children between the ages of 8 months and 19 months who are at increased risk of severe RSV disease, such as children who are severely immunocomp­romised, a dose is recommende­d in their second season.”

“This new RSV immunizati­on provides parents with a powerful tool to protect their children against the threat of RSV,” CDC Director Dr. Mandy Cohen said in a statement. “RSV is the leading cause of hospitaliz­ations for infants and older babies at higher risk, and today we have taken an important step to make this life-saving product available.”

Two vaccines against RSV also were given the green light earlier this summer for older adults. In June, the CDC endorsed an advisory group’s recommenda­tion for new RSV vaccines for those 60 and older, a decision the CDC said should be based on a patient’s discussion with their health care provider on whether the vaccinatio­n is right for them. Those vaccines are being offered by GSK and Pfizer.

Flu shots

The updated flu vaccinatio­n formula has been set for this fall. The CDC suggests the best times to get vaccinated against the flu are in September and October.

Getting vaccinated in August is not recommende­d for most people, the CDC said, unless there is reason to expect the person can’t get vaccinated in September or October. There are some exceptions: Pregnant people in their third trimester may want to get a flu vaccine in August to help ensure their newborn babies are protected because they’re too young to get a flu shot, the CDC said.

Everyone 6 months and older should get the annual flu shot, the CDC said, a recommenda­tion that has remained consistent since 2010.

 ?? ROGELIO V. SOLIS / ASSOCIATED PRESS (2022) ?? A resident of Jackson, Miss., receives a Pfizer booster shot Feb. 8, 2022, at a vaccinatio­n site. An updated COVID shot may be available this fall.
ROGELIO V. SOLIS / ASSOCIATED PRESS (2022) A resident of Jackson, Miss., receives a Pfizer booster shot Feb. 8, 2022, at a vaccinatio­n site. An updated COVID shot may be available this fall.

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