Las Vegas Review-Journal

One nasty side effect of liver disease

- Email questions for Mehmet Oz and Mike Roizen to youdocsdai­ly@sharecare.com.

About one out of nine adults in America say they’re experienci­ng cognitive decline — a potential precursor of dementia. Mild cognitive decline affects 22 percent of folks 65 and older, while almost 10 percent of seniors have full-blown dementia, according to a study published in JAMA Neurology.

But sometimes cognition problems are a symptom of another condition — and can be reversed or avoided altogether. A new study in JAMA reveals that up to 10 percent of so-called dementia cases may really be a side effect of liver disease, which often goes undiagnose­d.

Around 100 million Americans have nonalcohol­ic fatty liver disease (NAFLD), which can lead to fibrosis, cirrhosis and hepatic encephalop­athy (HE). That can trigger neurologic­al disruption­s, as the liver loses its ability to filter brain-damaging toxins from the body. NAFLD is caused by obesity, Type 2 diabetes, elevated LDL cholestero­l and insulin resistance.

Upgrading your nutritiona­l choices and increasing your physical activity level can slow or reverse early-stage NAFLD — and protect your brain.

The researcher­s in the JAMA study concluded that any patient with dementia should be screened for cirrhosis to uncover “reversible factors associated with cognitive impairment, such as HE.” Long before you develop cirrhosis, if you’re noticing cognition problems, talk with your doctor about being screened for NAFLD and other liver disorders, so you can protect your brain from collateral damage.

Pump up your iron

According to the American Medical Associatio­n, the more than 10 million people in the United States with iron deficiency (half have iron-deficiency anemia) need to increase intake of heme iron from animal sources and nonheme iron from plants. Animal sources include fish and poultry. Nonheme sources are green, leafy vegetables, beans and nuts, as well as tofu, dates, figs and raisins. Nonheme iron is less well-absorbed, but you can increase absorption by eating citrus fruits or taking a vitamin C supplement along with your iron-supplying foods.

Low levels of iron lead to fatigue and lightheade­dness because there’s a lack of oxygen-transporti­ng red blood cells in your body. Iron is also needed to produce various hormones and for brain developmen­t. Severe deficiency is associated with a fast heartbeat, shortness of breath, a sore tongue, extreme fatigue and cold hands and feet.

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DR. OZ AND DR. ROIZEN HEALTH ADVICE

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