Los Angeles Times (Sunday)

How the U.S. drug crisis entered the ‘synthetic era’

Trafficker­s are pushing synthetics such as fentanyl, because the market is demanding higher-potency drugs

- By Sam Quinones Sam Quinones,

Ain Venice in September, four people overdosed from what they thought was cocaine, three of them dying before paramedics arrived. The cocaine they used reportedly contained fentanyl.

The deaths were another example of what has taken place across the U.S. over the last few years as we have entered what I call the synthetic era of drugs — street dope made with chemicals; no plants involved. Synthetic drugs of various kinds have been around for decades, but none have come close to the supply and threat of the two staples now coming up from Mexico: fentanyl and methamphet­amine. And with synthetic drugs, as with most other products both legal and illegal, supply shapes demand.

I suspect this era will be with us for some time, because synthetic drugs make huge business sense to trafficker­s. They no longer need land, irrigation, pesticides or farmworker­s to grow drugs — they can produce them in makeshift labs or industrial warehouses. With no need to plan around weather and seasons, they can make these drugs year-round, provided they have enough chemicals. Synthetic drugs are quicker to make, and in the case of fentanyl, easier to smuggle because so little of it is needed to make extraordin­ary profits.

Key to the traffickin­g equation are shipping ports, which provide access to the world’s chemical markets and the ingredient­s needed to make synthetic drugs. Combine that with the impunity Mexican trafficker­s enjoy — ensured by corruption in that country and the guns smuggled there from ours — and the result is potent dope in the staggering quantities we see now across the U.S.

The Drug Enforcemen­t Administra­tion reported in September that it had already seized 9.5 million fentanyl-laced counterfei­t pills this year — more than it had in the two prior years combined. Some 40% of the seized pills had deadly quantities of the drug. Mexicanmad­e meth is so prevalent that its street price has collapsed to the lowest ever seen — typically between $1,500 and $3,000 a pound, down from roughly $10,000 and more per pound less than a decade ago.

A relentless supply is a reason drug dealers mix a hyper-potent drug like fentanyl into whatever they’re selling, even at the risk of killing their customers.

Fentanyl has become so commonplac­e that dealers now use it the way we use salt on our food. They liberally sprinkle it into anything they’re selling: cocaine, methamphet­amine and, in some rare cases, marijuana. They are motivated by the belief that fentanyl can boost the potency of any drug.

This is particular­ly true of cocaine. Many people across America have been dying from overdoses on cocaine they didn’t know was laced with fentanyl. This has been a major cause of an increase in opioid-overdose deaths among African Americans in particular. Prior to fentanyl, the opioid epidemic primarily affected white people.

Dealers also understand some basic truths about the drug-addicted brain that have emerged from advances in neuroscien­ce in the last two decades. Our brains contain elaborate systems that warn us of danger, of imminent threat of death. Without these systems, we would never have survived as a species.

Drugs of abuse have proved to mute these essential systems like nothing else. They hijack these parts of our brain so that they no longer warn us of imminent death. Instead, these complex neural systems, when on drugs, betray us and work in favor of dope, allowing the drug to convince us we can function only with it — even as it kills us. Like a parasite that will kill its host.

Dealers know that to the drugaddict­ed mind, an overdose is not a warning; it’s an advertisem­ent. An overdose or a death is notice that a dealer has especially potent dope for sale. This is why dealers have determined it makes good business sense to mix fentanyl into other drugs, even knowing the concoction may kill a customer or two.

For dealers, there is another advantage to adding fentanyl to cocaine or meth: It can turn an occasional buyer into an opioid-addicted daily customer who needs the drug to prevent sickness from withdrawal. And given the competitio­n among dealers created by all this supply, once one dealer adds fentanyl to whatever he’s selling, his competitor­s must follow suit or lose customers.

Many addicts won’t buy any drugs that don’t include fentanyl. One mid-level dealer I met recently gave her wholesaler some fentanyl test strips — which are intended to warn a user of the presence of fentanyl. In this case, she wanted the wholesaler to use the strips to make sure that whatever he bought included fentanyl.

For those addicted to fentanyl, heroin isn’t potent enough to keep the withdrawal sickness away, say many people I’ve spoken to. That is one reason heroin is disappeari­ng from U.S. streets and opium-poppy farmers in Mexico are in crisis as trafficker­s transition from a bulky plant to an easy synthetic.

Today, street addicts commonly have several drugs in their systems, often coming from one source. “What we call heroin has probably got everything but heroin in it,” a user in Eastern Tennessee told me recently.

Today’s quantities of synthetic drugs have brought to an end the era of “recreation­al drug use.” That concept belongs to a past when drugs were far more expensive, harder to procure, less potent and more forgiving; people could stay alive for decades while still using heroin.

Now, every line of cocaine, every “pill” at a party is an invitation to Russian roulette. On the streets of America, there’s no such thing as a long-term fentanyl user.

a former Los Angeles Times reporter, is the author of “Dreamland: The True Tale of America’s Opiate Epidemic” and “The Least of Us: True Tales of America and Hope in the Time of Fentanyl and Meth,” which will be published Tuesday.

 ?? ?? is a contributi­ng artist to Opinion. He blogs daily at https://stevebrodn­er.substack.com/. He is at work on a graphic book, “Living and Dying in America: a Daily Chronicle
is a contributi­ng artist to Opinion. He blogs daily at https://stevebrodn­er.substack.com/. He is at work on a graphic book, “Living and Dying in America: a Daily Chronicle

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