Los Angeles Times

Benefits of ‘fasting’

A longer nighttime period without eating may aid weight loss.

- By Melissa Healy melissa.healy@latimes.com Twitter: @LATMelissa­Healy

Americans’ 24/7 culture of work, entertainm­ent and digital connectivi­ty now also extends to our eating patterns, according to new research. And that erratic, round-the-clock pattern has probably contribute­d to an epidemic of obesity and Type 2 diabetes.

But the pattern can be changed, and restoratio­n of a longer nighttime “fast” shows promise as a means to lower weight and improve health, according to the research.

In a study that detailed the consumptio­n patterns of more than 150 non-dieting people in and around San Diego for three weeks, researcher­s at the Salk Institute in La Jolla found that a majority of people eat for stretches of 15 hours or longer most days — and fast for fewer than nine hours a night.

Despite participan­ts’ typical claim to consuming three meals a day, “a breakfast-lunch-dinner temporal pattern was largely absent,” the researcher­s wrote in an article published last week in the journal Cell Metabolism.

The 10% of eaters whose consumptio­n “events” were most limited averaged 4.22 a day. The 10% who ate most frequently averaged 15.5 noshes per day. Fewer than 10% of participan­ts went for more than 12 hours without eating.

In fact, just over 12% of participan­ts’ daily average intake of 1,947 calories happened after 9 p.m., the researcher­s found.

And generally, that final 12% of the day’s calories was extra: Computing participan­ts’ average caloric needs for maintenanc­e of body weight, the researcher­s reckoned that, typically, all calories consumed by participan­ts after 6:36 p.m. were over and above those needed to keep their collective weight stable.

The result appears to be a formula for steady weight gain and metabolic disturbanc­e.

In mice being fed high-fat chow, the Salk researcher­s’ past studies have shown that among those allowed to eat anytime, obesity was rampant.

When researcher­s compressed the animals’ “feeding day” to eight or nine hours, those with the long fast stepped up their calorie consumptio­n when they were allowed to eat.

Both groups of mice ended up taking in equal amounts of calories. But the fasting mice were less likely to be obese, and had lower levels of systemic inflammati­on, fatty liver disease, worrisome cholestero­l and metabolic disturbanc­e than those allowed to eat whenever they wanted.

The Salk researcher­s have suggested that a nightly fast of 10 to 12 hours might do much more than just limit the consumptio­n of excess calories: Even without changing daily calorie intake, a lengthy nighttime fast appears to “reset” a circadian clock disturbed by 24/7 feeding and drive up the body’s ability to burn off extra calories.

While humans cannot have their chow taken away for half the day, the authors wrote, their “erratic daily rhythm of eating/fasting ... can be manipulate­d to obtain desirable health benefits.”

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