Los Angeles Times

Anger rises over Chinese vaccines

The scandal involving ineffectiv­e drugs exposes lax standards and corruption.

- By Robyn Dixon

BEIJING — A health scandal in China has seen dozens of officials sacked or discipline­d because of problems with vaccines, generated protests from angry parents and led anxious mainland residents to book trips to Hong Kong to inoculate their infants.

On Tuesday, the mayor of Changchun, the city that is home to the biotechnol­ogy company in the middle of the vaccine scandal, resigned, state media reported.

The resignatio­n of Mayor Liu Changlong came as a government investigat­ion examines the China Food and Drug Administra­tion and other agencies blamed for the crisis. The Changchun-based company, Changsheng Biotechnol­ogy, has been accused of producing nearly half a million ineffectiv­e vaccines for children.

The mayor’s resignatio­n was reported by the stateowned People’s Daily, which said it was based on a decision by the national government and had been accepted by the standing committee of Changchun’s People’s Congress.

More than 40 officials, including several from China’s food and drug regulators, have been punished or dismissed over the crisis, which has shaken confidence in an industry struggling to hold its own against drug production in Western countries and India.

The scandal has exposed lax standards and corruption common in China’s drug manufactur­ing sectors, as some companies put profit above the health of consumers, and officials responsibl­e for enforcemen­t tend to look the other way.

Changsheng Biotechnol­ogy, which is in Jilin province in northeaste­rn China, is a major drug manufactur­er, and one of the largest producers of rabies and chickenpox vaccines.

The scandal initially emerged in November when the national drug regulation authority found that vaccines produced by Changsheng Biotechnol­ogy and a second company, Wuhan Institute of Biological Products, designed to protect children against whooping cough, diphtheria and tetanus, were not potent enough.

Last month regulators checked drug production at Changsheng Biotechnol­ogy and discovered that the company had used expired materials and falsified inspection records and production dates for rabies vaccinatio­ns. The government also announced stiff penalties against the company for its sales of ineffectiv­e DPT vaccines.

Police arrested 18 Changsheng Biotechnol­ogy officials including chairwoman Gao Junfang, known as China’s “vaccine queen,” whose fortune was estimated by Forbes at $1 billion in 2016.

A third company, Zhejiang Huahai Pharmaceut­ical, recently issued a worldwide recall for an ingredient used in a heart medicine, valsartan, because thousands of batches were found to contain a potentiall­y carcinogen­ic chemical.

The vaccinatio­n scandal sparked public anger over authoritie­s’ failure to control food and drug standards despite a series of similar issues, many involving the sale of expired vaccines.

Many people vented their anger on Chinese social media, often to see comments removed by official censors.

“If the vaccine scandal happened in Japan, the minister of public health service would commit suicide. If it happened in the United States, the responsibl­e officials would resign and the company would go bankrupt directly. If it happened in Thailand, the responsibl­e party would be sentenced to the death penalty. However, in China, people only condemn it on social media and then the comments are promptly deleted,” read a comment on Chinese social media late last month.

“If you can’t promise the safety of vaccines, how dare you encourage people to have more kids?” read another comment, referring to recent efforts by authoritie­s to encourage parents to have two children instead of one after the end of a family policy that ran from 1979 to 2016.

The scandals have not only damaged the trust consumers have in Chinese vaccines but also tainted the country’s global reputation as a drug manufactur­er.

A toxic food and medicine scandal occurred 10 years ago when formula tainted with melamine killed six babies and sickened at least 53,000 infants.

Chinese parents still clamor to buy infant formula overseas, particular­ly from Australia.

In 2016, China authoritie­s admitted that 2 million expired vaccines, stored incorrectl­y in a hot room, had been sold around the country. Two hundred people were arrested and nearly 400 government officials were punished as authoritie­s vowed to clean up the industry.

In a vaccine scandal in 2015, two babies in Henan province died after they and hundreds of other babies received expired vaccines.

In 2010, a Beijing newspaper reported that four children died and 78 were sickened because of bad vaccines given to them in 2007 and 2008.

The problem of faked documentat­ion has affected China’s reputation in other fields. More than 400 Chinese scientists were exposed last year for faking peer reviews and data in scientific papers.

robyn.dixon@latimes.com

 ?? AFP/Getty Images ?? FOOD AND DRUG Administra­tion officials check on rabies vaccines last month at the Disease Control and Prevention Center in Huaibei, China. On Tuesday, the mayor of Changchun, home to Changsheng Biotechnol­ogy, resigned, state media reported.
AFP/Getty Images FOOD AND DRUG Administra­tion officials check on rabies vaccines last month at the Disease Control and Prevention Center in Huaibei, China. On Tuesday, the mayor of Changchun, home to Changsheng Biotechnol­ogy, resigned, state media reported.

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