Los Angeles Times

Social science, not hard science

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Re “Weight gain isn’t just a matter of calories,’ Opinion, Nov. 15

Dr. David S. Ludwig misses the boat with his hypothesis that processed carbohydra­tes stimulate more insulin, forcing glucose into fat cells and depriving the rest of the body of calories, thus resulting in hunger.

It has already been proved that excess insulin results in hypoglycem­ia and rebound hunger. Any diabetic is very conscious of this fact with his or her insulin injections.

Ludwig’s evidenceba­sed study of the metabolism of individual­s whose carbohydra­te intake was controlled has permeated the media as gospel. But his study had only 164 subjects divided into three groups. A better study can be done on laboratory animals with a controlled diet and environmen­t and in the numbers required for credible results.

Too much money and resources are wasted on medical studies by researcher­s seeking grants to justify their position in the medical hierarchy. Common sense and experience should count for more in medicine, which is more a social science than a pure one. Jerome P. Helman, MD Venice The writer is a gastroente­rologist who specialize­s in nutrition.

Ludwig questions the “eat less, move more” theory of weight loss yet confesses that his hypothesis needs, at least, replicatio­n by other authoritie­s.

We do know this much: You can’t make something out of nothing. The body needs energy (calories). If the energy is not burned, it accumulate­s.

Think of a battery being charged. It can’t be overcharge­d, so when it’s full, it’s full. This is not so in the case of the human body, where any “overcharge” accumulate­s as fat.

The rest is up for discussion. Louis H. Nevell Los Angeles

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