Los Angeles Times

Not all hand sanitizers are alike. Some are dangerous

Any with methanol are a threat, especially to children, FDA says.

- By Melissa Healy

In the era of COVID-19, hand sanitizer has become such an ever-present commodity that we have come to take its virtues — and its safety — for granted.

No longer. The Food and Drug Administra­tion is warning Americans that certain hand-sanitizing products sold under a wide range of labels could be dangerous — or even fatal.

Drinking them could cause blindness, liver and kidney damage, or death. So could slathering it on one’s skin, since it passes quickly through the skin and into tissues beneath. Children are particular­ly vulnerable to potential harm from the stuff.

The culprit is methanol, a poor cousin of isopropyl alcohol or ethyl alcohol, the approved active ingredient­s in hand sanitizing products. Starting in late July, the FDA began detecting what it called a “sharp increase” in hand sanitizers that claimed to be made with ethyl alcohol but were contaminat­ed by methanol.

Methanol smells, feels, tastes and evaporates like ethyl alcohol, the inebriate that spikes cocktails, and isopropyl alcohol, which cleans wounds and soothes muscles. While ethyl and isopropyl alcohol have two carbon atoms, methanol has just one.

When consumed or absorbed through the skin, methanol’s first effects — including confusion, heavy breathing, slurred words and altered perception — will be familiar to anyone who has sat on a barstool for too long.

But when metabolize­d by the human body, methanol makes formic acid and formaldehy­de, both of which attack the nervous system. The optic nerve is the first line of defense to fall, and a victim of methanol poisoning will often begin to experience “snowy” vision and potentiall­y permanent blindness. In fact, this is the origin of the term “blind drunk.”

In some cases, death by poisoning can ensue.

Sometimes called wood alcohol, methanol is widely used in antifreeze, varnishes, cologne, copying machine fluids, paint and fuel. It can also be the unintended product of alcohol production when quality control is lacking.

Around the world, methanol is widely consumed as an intoxicant but also used in suicidal self-poisoning. Case studies abound in the medical literature of patients who treat fever, pain and other affliction­s with topical applicatio­ns of methanol, and wind up hospitaliz­ed.

Dr. William Banner, medical director of the Oklahoma Center for Poison and Drug Informatio­n, said that so far, tainted hand sanitizer has not caused a notable uptick in calls to poison control centers.

But as hand sanitizer becomes Americans’ go-to defense against coronaviru­s infection, health officials know it is being misused. Parents are slathering it not just on children’s hands but on their faces, arms and bodies as well, a practice Banner discourage­d. Those in search of a buzz are knowingly tippling it. Children and teens are tasting it out of curiosity or on a dare.

When sanitizer is tainted with methanol, such misuse could pose immediate dangers. And for children, who weigh much less than adults but have nearly as much skin, a dose of methanol could cause a rapid concentrat­ion to build up in tissues, Banner said. That could spell disaster, he warned.

A report published Wednesday by the U.S. Centers for Disease Control and Prevention highlighte­d the dangers of these products. Researcher­s combed through calls to poison control centers in Arizona and New Mexico in May and June and identified 15 cases of methanol poisoning tied to hand sanitizers. All of those patients were sick enough to be admitted to a hospital.

Nine of the victims required hemodialys­is to restore damage to their kidneys, and six had seizures while they were in the hospital. Four of the patients died, and another four were still hospitaliz­ed eight days after the surveillan­ce period ended. Of the seven patients who were discharged, three suffered some degree of permanent vision loss, according to the dispatch in the CDC’s Morbidity and Mortality Weekly Report.

The 115 hand-sanitizer products that the FDA has recalled have been sold at both retail and online stores. All but three were made in Mexico, and those imports are now blocked from entering the United States. But they are likely still to be in circulatio­n.

The FDA has posted a list of brands, marketing names and lots that it has recalled.

With names like Blumen,

LumiSkin, Scent Theory, Born Basic and Urbane Bath & Body, they are indistingu­ishable from the hand sanitizers recommende­d as a way to prevent the transfer of the coronaviru­s from hands to mucous membranes in the nose and mouth, where they can take up residence and replicate, often to ruinous effect.

“You really can’t identify methanol by smell or sight,” said Banner, a past president of the American Assn. of Poison Control Centers.

He added that adults should be careful not to go overboard in covering their children with any hand sanitizer, since its alcohol can be absorbed through the skin.

But if a child who has been doused, or who may have sneaked off and sipped the stuff, has an unexplaine­d change in behavior such as heavy breathing or acting inebriated, call the local Poison Control Center at (800) 222-1222. Experts there can check whether a hand sanitizer in use is among those that have been recalled.

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