Los Angeles Times

Why ‘ herd immunity’ can’t save us from COVID- 19

Allowing a large number of infections would lead to more deaths, experts warn.

- By Aneri Pattani Pattani writes for Kaiser Health News, an editoriall­y independen­t program of the Henry J. Kaiser Family Foundation. It is not affiliated with Kaiser Permanente. KHN reporter Victoria Knight contribute­d to this report.

For a term that’s at least 100 years old, “herd immunity” has gained new life in 2020.

It made headlines last month when reports surfaced that Dr. Scott Atlas, a member of the White House Coronaviru­s Task Force and advisor to the president, recommende­d it as a strategy to combat COVID- 19. Atlas, a former chief of neuroradio­logy at Stanford who now focuses on healthcare policy, suggested the virus should be allowed to spread through the population so that people build up immunity, rather than trying to contain it through shutdown measures, according to the Washington Post.

At a town hall event a few weeks later, President Trump raised the idea himself, saying the coronaviru­s would simply “go away,” as people developed “herd mentality” — a slip- up that was understood to be a reference to the same concept.

Last month, Sen. Rand Paul ( R- Ky.) sparked a heated debate at a committee hearing when he suggested that the decline in COVID- 19 cases in New York City was due to herd or community immunity rather than public health measures, such as wearing masks and social distancing.

Dr. Anthony Fauci, the top U. S. infectious disease

official, rebuked Paul, pointing out that only 22% of the city’s residents have coronaviru­s antibodies.

“If you believe 22% is herd immunity, I believe you’re alone in that,” Fauci told the senator.

What is herd immunity?

Herd immunity, also called community or population immunity, refers to the point at which enough people are sufficient­ly resistant to a disease that an infectious agent is unlikely to spread from person to person. As a result, the whole community — including those who don’t have immunity — becomes protected.

People generally gain immunity in one of two ways: vaccinatio­n or infection. Vaccines have been the route to herd immunity for most diseases in recent history, including smallpox, polio, diphtheria and rubella.

For the most highly contagious diseases, such as measles, about 94% of the

population needs to be immunized to achieve that level of protection. For COVID- 19, scientists estimate the percentage falls between 50% to 70%.

Can we speed up herd immunity to end the pandemic?

Before the COVID- 19 pandemic, experts can’t recall an example in which government­s intentiona­lly turned to natural infection to achieve herd immunity. Generally, such a strategy could lead to widespread illness and death, said Dr. Carlos del Rio, an expert in infectious disease and vaccines at the Emory University School of Medicine.

“It’s a terrible idea,” Del Rio said. “It’s basically giving up on public health.”

The U. S. still has a long way to go to achieve herd immunity to the coronaviru­s that causes COVID- 19. A large study published last month in the medical journal Lancet found that fewer than 1 in 10 Americans have antibodies to SARS- CoV- 2, the formal name for the coronaviru­s. Even in the hardest- hit areas, such as New York City, estimates of immunity among residents are about 25%.

To reach 50% to 70% immunity would mean about four times as many people getting infected and an “incredible number of deaths,” said Josh Michaud, associate director of global health policy at the Henry J. Kaiser Family Foundation. Some of those who survive could suffer severe consequenc­es to their heart, brain and other organs, potentiall­y leaving them with lifelong disabiliti­es.

Is natural immunity better than a vaccine?

Some scientists say natural immunity may not be a feasible defense against COVID- 19.

Although most people presumably achieve some degree of protection against the coronaviru­s after being infected once, cases of people who recovered from COVID- 19 and were reinfected have raised questions about how long natural immunity lasts and whether someone with immunity could still spread the virus.

Even the method scientists are using to measure immunity — blood tests that detect antibodies to the coronaviru­s — may not be an accurate indicator of who is protected against COVID- 19, said Dr. Stuart Ray, an infectious disease expert at the Johns Hopkins University School of Medicine.

With so many unanswered questions, “we can’t count on natural herd immunity as a way to control this epidemic,” he said.

Vaccines, on the other hand, can be made to trigger stronger immunity than natural infection, Ray said. That’s why people who acquire a natural tetanus infection, for example, are still advised to get the tetanus vaccine.

The hope is that vaccines being developed for COVID- 19 will provide the same higher level of immunity.

But what about Sweden?

In the political debate around COVID- 19, proponents of a natural herd immunity strategy often point to Sweden as a model. Although the Scandinavi­an country imposed fewer economic shutdown measures, its death rate is less than that of the U. S., Paul said at the Sept. 23 Senate hearing.

But health experts — including Fauci during the same hearing — said that’s a f lawed comparison.

The U. S. has a much more diverse population, with vulnerable groups like Black and Latino people being disproport­ionately affected by the coronaviru­s, said Dr. Jon Andrus, an epidemiolo­gy expert at the George Washington University Milken Institute School of Public Health. The U. S. also has greater population density, especially on the coasts, he said.

Compared with those in other Scandinavi­an countries, Sweden’s death toll is much higher. It has had 5,895 deaths linked to COVID- 19 so far, according to data from Johns Hopkins University. That’s nearly 58 deaths per 100,000 residents — several times higher than the death rates of 5 or 6 per 100,000 in Norway and Finland.

A study by the country’s public health agency found that by late April only 7% of residents in Stockholm had antibodies for COVID- 19. In other Swedish cities, the percentage was even lower.

Those f indings mirror other studies around the globe. In several cities across Spain, Switzerlan­d and the U. S. — with the exception of New York City — less than 10% of the population had coronaviru­s antibodies by June, according to a study in JAMA Internal Medicine. And that was despite months of exposure and high infection rates.

So what’s the bottom line?

Natural herd immunity is an uncertain strategy, and attempts to pursue it could result in a slew of unnecessar­y deaths, medical experts say. A vaccine, whenever one becomes available, would offer a safer route to community- wide protection.

Until then, they emphasize there is still plenty to do to counter the pandemic. Wearing masks, practicing social distancing, handwashin­g and ramping up testing and contact tracing have all proved to help curb the virus’ spread.

 ?? Evan Vucci Associated Press ?? DR. SCOTT ATLAS, an advisor to President Trump on the coronaviru­s, suggested the virus should be allowed to spread through the population.
Evan Vucci Associated Press DR. SCOTT ATLAS, an advisor to President Trump on the coronaviru­s, suggested the virus should be allowed to spread through the population.

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