Los Angeles Times

Germany prepares for vaccine drive

Authoritie­s are about to start a nationwide program as country hits 1 million cases of the coronaviru­s.

-

TUTTLINGEN, Germany — Hulking gray boxes are rolling off the production line at a factory in the southern town of Tuttlingen, ready to be shipped to the front in the next phase of Germany’s battle against the coronaviru­s as it became the latest country to hit the milestone of 1 million confirmed cases Friday.

Man- sized freezers such as those manufactur­ed by family- owned f irm Binder GmbH could become a key part of the vast immunizati­on program the German government is preparing to roll out when the f irst vaccines become available next month.

That’s because one of the front- runners in the race for a vaccine is BioNTech, a German company that together with U. S. pharmaceut­ical giant Pfizer has developed a shot it says is up to 96% effective in trials but comes with a small hitch: It needs to be cooled to minus- 94 degrees Fahrenheit for shipping and storage.

Ensuring such low temperatur­es, colder than an Antarctic winter, is just one of the many challenges that countries face in trying to get their population­s immunized.

The effort has been compared to a military operation. Indeed, some countries, including Germany, are relying on military and civilian expertise to ensure the precious doses are safely transporte­d from manufactur­ing plants to secret storage facilities before being distribute­d.

Germany has benefited from the market power that

comes with being a member of the European Union. The 27- nation bloc’s executive commission — led by former German Defense Minister Ursula von der Leyen — has spearheade­d negotiatio­ns with vaccine makers, ordering more than a billion doses so far.

German officials have said the country hopes to secure up to 300 million doses from the EU orders and bilateral deals with three manufactur­ers in Germany, including BioNTech and Cure- Vac, a company based in Tuebingen that says its vaccine can be stored at regular refrigerat­or temperatur­es for up to three months. Its trials are not as far along, however, as those of Pfizer/ BioNTech and others.

The f igure of 300 million is contingent on all vaccines being developed making it to market. That would be more than enough to immunize

Germany’s population of 83 million, even if two shots are required, as seems likely.

How exactly the vaccine is delivered to patients differs from country to country. In Germany, the federal government has delegated the task to its 16 states, which are now working to build large vaccinatio­n centers.

The city- state of Berlin has drafted in Albrecht Broemme, a veteran of disaster management. The former Berlin fire chief later led Germany’s federal civil protection organizati­on THW, where he helped organize disaster relief operations for f loods, storms and quakes around the world.

The 67- year- old is now coordinati­ng the establishm­ent of six vaccine hubs in Berlin in a convention center, two former airports, an ice skating rink, a concert hall and an indoor cycle racetrack.

Authoritie­s want them ready by mid- December to begin vaccinatin­g more than 3,000 people per day at each location. With just a few minutes to deliver each shot and mindful of keeping the number of people in each center at a minimum, Broemme and his colleagues are devising a one- way f low system similar to that found in large retail stores.

Each site will be run by a medical aid group, such as the Red Cross, with volunteers to help register and guide people through the venue.

Like elsewhere, the f irst phase of vaccinatio­n in Berlin will probably focus on immunizing healthcare workers and vulnerable groups such as the elderly and those with chronic illnesses. About 20,000 people will be vaccinated each day, returning after three weeks for a booster shot.

Demand is likely to outstrip supply at first, but that will change as more vaccines come onto the market.

“We’re hopeful that approvals in the f ield of vaccinatio­n will be issued very quickly,” German Chancellor Angela Merkel told parliament on Thursday. “That won’t solve the problem immediatel­y, but there’s a light at the end of the tunnel.”

Broemme has said he expects four- f ifths of the vaccines initially available to need ultra- low cooling. That means every center will need a pharmacy that handles both the storage and thawing of vaccines.

At the other end of the country in Tuttlingen, Binder GmbH, one of hundreds of medical device manufactur­ers in the town, some with a history dating to the 19th century, is seeing demand for its freezers surge.

Priced at $ 15,500-$ 17,900, each device can keep tens of thousands of vials of vaccine at optimum temperatur­e, says Peter Wimmer, the company’s head of innovation.

“It’s plug and play,” he told the AP. “All you need is an electrical socket, switch it on, and the device is ready to go.”

Having the whole vaccinatio­n system ready to go at the touch of a button is a different matter, though.

It is still unclear who will administer the vaccines in Berlin. Unlike Britain, which has a centralize­d National Health Service organizing the immunizati­on drive, Germany is relying on doctors associatio­ns to provide the necessary medical staff.

Doerthe Arnold, a spokeswoma­n for the Berlin branch of Germany’s Assn. of Statutory Health Insurance Physicians, said it is still waiting for the state government to provide details on what will be required of doctors.

“Despite the positive feedback from doctors’ practices that they’re willing to help out even more, providing medical personnel for the six vaccinatio­n centers will be a challenge,” she said.

The limits of medical logistics were tested in spring, when huge worldwide demand for ventilator­s, therapeuti­c drugs, face masks and other protective equipment prompted bidding wars, bottleneck­s and reports of faulty products.

Global logistics company DHL estimates that to provide worldwide coverage of vaccines over the coming two years may require 15,000 f lights.

“The challenge is the sheer number of doses and the fact that it’s not clear which vaccine needs to go where,” Sabine Hartmann, a DHL spokeswoma­n, told the AP. “It’s not something a single company can do on its own. All logistics companies have to work together on this.”

 ?? Matthias Schrader Associated Press ?? AN EMPLOYEE OF Binder GmbH checks an ultra- low- temperatur­e freezer. Such freezers will be in high demand for a COVID- 19 vaccine that must be cooled at minus- 94 degrees Fahrenheit for shipping and storage.
Matthias Schrader Associated Press AN EMPLOYEE OF Binder GmbH checks an ultra- low- temperatur­e freezer. Such freezers will be in high demand for a COVID- 19 vaccine that must be cooled at minus- 94 degrees Fahrenheit for shipping and storage.

Newspapers in English

Newspapers from United States