Miami Herald

Drug executives: Big jump in vaccine supply is coming soon

- BY MATTHEW PERRONE AND LAURAN NEERGAARD

COVID-19 vaccine makers told Congress on Tuesday to expect a big jump in the delivery of doses over the coming month, and the companies insist they will be able to provide enough for most Americans to get inoculated by summer.

By the end of March, Pfizer and Moderna expect to have provided the U.S. government with a total of 220 million vaccine doses, up sharply from the roughly 75 million shipped so far.

“We do believe we’re on track,” Moderna President Stephen Hoge said, outlining ways the company has ramped up production. “We think we’re at a very good spot.”

That’s not counting a third vaccine, from Johnson & Johnson, that’s expected to get a green light from regulators soon. The Biden administra­tion said Tuesday that it expects about 2 million doses of that vaccine to be shipped in the first week, but the company told lawmakers it should provide enough of the single-dose option for 20 million people by the end of March.

Looking ahead to summer, Pfizer and Moderna expect to complete delivery of 300 million doses each, and J&J aims to provide an additional 100 million doses. That would be more than enough to vaccinate every American adult, the goal set by the Biden administra­tion.

Two other manufactur­ers, Novavax and AstraZenec­a, have vaccines in the pipeline and anticipate eventually adding to those totals.

Asked pointedly if they face shortages of raw materials, equipment or funding that would throw off those schedules, all of the manufactur­ers expressed confidence that they had enough supplies and had already addressed some of the early bottleneck­s in production.

“At this point I can confirm we are not seeing any shortages of raw materials,” said Pfizer’s John Young.

The hearing by a House subcommitt­ee came as U.S. vaccinatio­ns continue to accelerate after a sluggish start and recent disruption­s caused by winter weather. More than 44 million Americans have received at least one dose of either the Pfizer or Moderna vaccine, and about 1.4 million per day got a first or second dose over the past seven days, according to the CDC.

But state health officials say demand for inoculatio­ns still vastly outstrips the limited weekly shipments provided by the federal government.

“The most pressing challenge now is the lack of supply of vaccine doses,” Rep. Diana DeGette, a Colorado Democrat, said as she opened the hearing. “Some of the companies here today are still short of the number of doses they promised to initially deliver when they last testified before this subcommitt­ee in July.”

Both Pfizer and Moderna failed to meet delivery quotas for the initial doses of their vaccines late last year. That has prompted Congress to scrutinize the companies’ plans for vaccine developmen­t and delivery, which they noted benefited from $16 billion in federal funding.

Nearly 14% of Americans have received at least an initial dose of the two-shotregime­n vaccines from Pfizer and Moderna.

Even with no manufactur­ing or supply interrupti­ons, other issues could delay or block the U.S. from vaccinatin­g 70% to 80% of its population — the critical threshold needed to neutralize COVID-19 spread.

About 1 in 3 Americans say they definitely or probably will not get the vaccine, according to a recent poll from The Associated PressNORC Center for Public Affairs Research. Concerns about safety were the reason most frequently cited for vaccine hesitancy, despite few serious side effects reported with the currently available vaccines.

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