Milwaukee Journal Sentinel

Study: Pregnant women with COVID-19 could infect fetus

- Marilynn Marchione

A small study strengthen­s evidence that a pregnant woman infected with the novel coronaviru­s might spread it to her baby.

Researcher­s from Italy said Thursday that they studied 31 women with COVID-19 who delivered babies in March and April. They found signs of the virus in several samples of umbilical cord blood, the placenta and, in one case, breast milk.

Women shouldn’t panic. This doesn’t mean there’s viable virus in those places and “it’s too early to make guidelines” or to change care, said the study leader, Dr. Claudio Fenizia, an immunology specialist at the University of Milan.

But it does merit more study, especially of women who are infected earlier in their pregnancie­s than these women, said Fenizia, who discussed the results at a medical conference held online.

Since the start of the pandemic, doctors have wondered whether in-thewomb infection could occur.

The new study involved women at three hospitals during the height of the outbreak in northern Italy. The virus’s genetic material was found in one umbilical cord blood sample, two vaginal swabs and one breast milk sample. Researcher­s also found specific, anti-coronaviru­s antibodies in umbilical cord blood and in milk.

In one case, “there’s strong evidence suggesting that the newborn was born already positive because we found the virus in the umblilical cord blood and in the placenta,” Fenizia said.

In another, a newborn had antibodies to the coronaviru­s that do not cross the placenta, so they did not come from the mother and were “due to direct exposure of the fetus to the virus,” Fenizia said.

In any case, the possibilit­y of fetal infection seems relatively rare, he said. Only two of the newborns tested positive for the coronaviru­s at birth and neither became ill from it.

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