New Haven Register (Sunday) (New Haven, CT)

‘Playing catch-up’ on opioids

Doctors slow to adopt drug-aided therapy

- By Peggy McCarthy

William Evans grew up in Brookfield, a high school tennis player from a family with an Ivy League pedigree. By the time he was working at his first job after college, he was addicted to opioids, spending $25,000 in less than a year and driving to Philadelph­ia twice a week to buy drugs on the street.

Now 37, Evans hasn’t used illegal drugs since 2006. He is married and has a 3-year-old daughter, a home in Trumbull, and a sales job at a software company. He attributes his sobriety to counseling and medication to treat his addiction.

“It’s allowed me to live a life,” he said.

Research shows that medication-assisted treatment, or MAT, for opioid addiction is effective because it eliminates drug cravings, but the use of MAT in Connecticu­t is not keeping up with the epidemic, said Dr. David Fiellin, director of the Yale Program in

Addiction Medicine, who works with the state to address the opioid crisis.

“We are, at some level, playing catch-up,” Fiellin said. “I think it’s going to take, unfortunat­ely, a number of years” to meet the need for MAT in the state, he said.

The need and treatment gaps

Connecticu­t ranks in the top 10 of states with the highest rates of fatal opioid overdoses, according to the National Institute of Drug Abuse, which said the state rate more than quadrupled from 5.7 deaths per 100,000 people in 2012 to 24.5 in 2016. In 2017, 1,038 people died of opioid overdoses in Connecticu­t, up from 729 in 2015 and 917 in 2016, state medical examiner figures show.

There are no “reliable estimates” of the number of Connecticu­t residents with opioid use disorder, Fiellin said. Roughly 2 million people are addicted to opioids in the U.S., with 72,000 fatalities in 2017, according to preliminar­y figures from the Centers for Disease Control and Prevention.

Three drugs have federal approval for treatment of opioid use disorder. They are methadone, administer­ed only in federally regulated sites; buprenorph­ine, for which medical profession­als must be trained before prescribin­g; and naltrexone, for which training isn’t required, but is in limited use because patients must be drug-free for seven days before taking it.

Addressing opioid addiction with medication-assisted treatment reduces overdoses, illicit drug use, cases of HIV and criminal behavior, Fiellin said. The practice is endorsed by federal health agencies and the state government. Advocates contend that since OUD is a chronic brain disease, it should be treated with medication as other diseases are.

About 3,800 practition­ers are licensed in Connecticu­t to prescribe buprenorph­ine, according to federal figures provided by the state Department of Consumer Protection. That number includes doctors, psychiatri­sts, nurse practition­ers, and physician assistants who work in private practices, emergency rooms, health clinics and substance abuse facilities.

But state and local health officials say there’s a dearth of primary care physicians who treat opioid use disorder with MAT. Also, few residentia­l treatment programs use MAT, opting for no-medication, an approach that increases overdose risk after discharge, Fiellin said.

Private practition­ers in addiction care are mainly psychiatri­sts and addiction

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1 A front-page story in Saturday’s Register, “In search of a plastic-free Shoreline,” was missing a byline. The story was written by Sarah Page Kyrcz.

1 A story in Saturday’s Register incorrectl­y stated the status of Josh Balter. Balter ran for the state Senate to represent the 34th District. specialist­s, not primary care doctors, experts say.

Dr. J. Craig Allen, medical director at Rushford, which operates addiction and mental health services at facilities across the state, has conducted buprenorph­ine training but says, “There are so few people actually prescribin­g the medication.” He said the “challengin­g behaviors” of people with OUD can deter primary care physicians.

But not Dr. Peter Rostenberg, of New Fairfield, a primary care doctor and internist who has been using MAT since 2003. He has prescribed Suboxone, a brand name of buprenorph­ine, to some 500 patients. As part of their treatment, he requires them to attend group therapy. “Isolation is addiction and socializat­ion is recovery,” Rostenberg said.

Rostenberg, who received a federal award for his OUD treatment, said his typical patients come to him “in desperatio­n,” often after being unsuccessf­ul in residentia­l abstinence programs. Generally, after taking buprenorph­ine, they “flourish in life,” he said. “They feel really good because they are losing that craving.”

Emergency department­s in 11 acute care hospitals and VA Connecticu­t Healthcare now prescribe buprenorph­ine, which also eases withdrawal symptoms. In the first four months of 2018, there were at least 3,090 ER visits for suspected drug overdoses among CT residents, the state Public Health Department reports.

Of the state’s 19 correction­al facilities, two prisons and three jails provide methadone treatment, with a fourth jail to be added within six months. In 2016, 52 percent of fatal opioid overdose victims were incarcerat­ed at some point, according to the state Department of Correction. Dr. Kathleen Maurer, the agency addiction services director, said the department’s treatment efforts, limited by finances, is “a work in progress.”

Outpatient clinics in New Haven and New Britain offer MAT to newly released inmates with OUD and physical and mental illnesses.

Fiellin said treatment gaps are statewide, but are most acute in northweste­rn and northeaste­rn Connecticu­t. Even in cities with several treatment options, there is not a sufficient mix of services, which can mean long waits, inadequate hours of operation and insurance hurdles, he said.

About 50 percent of the people being treated for OUD are covered by Medicaid, 30 percent by private insurance, and the rest either have no insurance or are covered by federal veterans’ benefits, Fiellin said.

Lauren Siembab, MAT director for the state Department of Mental Health

and Addiction Services, said she knows of just 15 primary care doctors who take Medicaid and treat OUD with medication.

Local efforts to use MAT

The federal government, to stem the rising opioid crisis, has given Connecticu­t $15.5 million in recent grant money.

In southeaste­rn Connecticu­t, the nine-town Ledge Light Health District is using federal dollars in an aggressive effort to increase MAT; expand use of naloxone, an overdose reversal drug; provide clean syringes to reduce blood-borne diseases; and hire “recovery navigators,” who go into communitie­s looking for people with OUD to refer them to MAT and social service programs.

Jennifer Muggeo, the district’s supervisor of special projects and cofacilita­tor of the region’s Opioid Action Team, said that from the start of the navigators program in April through August, 80 people with OUD were located and at least 50 began treatment. In 2016, 40 people in the district died from opioid overdoses, she said.

“We need to expand access to treatment and people should have a choice,” Muggeo said.

Allen, of Rushford, said the lack of primary care doctors treating OUD also stems from a historic absence of addiction curricula in medical schools and post-graduate training, a situation that “doesn’t make sense,” he said, explaining that often diseases are worsened when a patient also has a substance abuse disorder.

Medical schools at Yale, Quinnipiac and the University of Connecticu­t have addiction in their curricula.

Evans’ recovery

For Evans, life “drasticall­y changed for the better” after getting treatment from Rostenberg. Evans said he began snorting opiates in college and eventually became consumed with getting increasing amounts as his tolerance grew. He spent the $10,000 his grandmothe­r gave him for graduation and exhausted his salary at a car rental company. “I knew I was going to hit a wall where I was not going to be able to support this addiction anymore,” he said.

Evans said his addiction robbed him of the ability to maintain relationsh­ips, save money and achieve goals, and made him unreliable. Suboxone, he said, doesn’t make him high, but takes away his cravings and allows him to feel normal.

Counseling and support groups helped him change, he said. He stopped associatin­g with friends who took drugs, changed his phone number so dealers couldn’t reach him, and avoided bars. Two friends have died of overdoses, Evans said.

He’s been married for five years. He dotes on his daughter. He plays tennis, golf and guitar. And, he said, “people can count on me.”

The state Department of Mental Health and Addiction Services provides informatio­n on medication-assisted treatment options. For informatio­n, visit https://bit.ly/2xdMj8d

The Substance Abuse and Mental Health Services Administra­tion provides a list of 1,137 doctors, nurse practition­ers and physician assistants who are licensed to administer buprenorph­ine and have requested to be listed. To find CT licensed practition­ers, visit https://bit.ly/2xfciw2

Peggy McCarthy is a Connecticu­t Health I-Team writer. This story was reported under a partnershi­p with www.c-hit.org.

 ?? Derek Torrellas / Conn. Health I-Team ?? Brookfield native William Evans outside his home in Trumbull.
Derek Torrellas / Conn. Health I-Team Brookfield native William Evans outside his home in Trumbull.

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