Vargas: ABC you later — after 22 yrs.

ELIZABETH VARGAS will be giving her final sign off from ABC News after 22 years on the network.

The longtime anchor announced on Friday that she would step down from “20/20” in May as the show wraps up its 40th season.

“I want you to hear some news about me, from me. I will be leaving ABC News, and ‘20/20’ at the end of this historic 40th season. It has been a profound privilege to be the anchor of ‘20/20’ for 14 years, and a true honor to work with each and every one of you,” she wrote in a letter to staff on Friday.

Vargas (photo) co-hosted with David Muir, after she replaced Barbara Walters.

The 55-year-old got her start on the network in 1996 as a newsreader for “Good Morning America” — and was in the anchor chair for the Saturday “World News Tonight” shows a year later.

In 2004, Vargas was named co-anchor of 20/20 and a year later she joined ABC World News Tonight.

Vargas has been open about her struggle with sobriety, she checked into rehab for her alcoholism in 2014.