Orlando Sentinel

Will citrus bergamot help lower cholestero­l level?

- By Joe Graedon and Teresa Graedon King Features Syndicate In their column, Joe and Teresa Graedon answer letters from readers. Send questions to them via peoplespha­rmacy.com.

Q: I have had success taking red yeast rice to lower my cholestero­l. However, it’s not quite as effective now as in the beginning. My nutritioni­st suggested trying citrus bergamot. Is there research to back this up?

A: We were surprised to learn that Citrus bergamia, the bergamot orange, acts on the same enzyme as red yeast rice and statins to lower cholestero­l (Fitoterapi­a, April 2011). Scientists have conducted a handful of studies to determine whether this fruit or its extract would be effective for treating high cholestero­l. One study of 80 individual­s found that a bergamot extract (Bergavit R) lowered cholestero­l significan­tly during the six-month study (Frontiers in Pharmacolo­gy, Jan. 6, 2016). This trial was not placebo-controlled, however. And some other studies have not confirmed the lipid-lowering benefits of bergamot.

Some people complain that drinking Earl Grey tea can trigger muscle cramps. Since bergamot provides the distinctiv­e flavoring for this tea, you should be alert for this complicati­on.

Q: Seven of my fingernail­s have become concave. The nails have always been quite thin. Is there a cure for this? Are there any special foods or vitamins that might help?

A: You are describing what may be “koilonychi­a.” One way to test for this condition is to put a drop or two of water on the affected nail. If the water does not run off immediatel­y, you could indeed have this condition.

Concave or spoonshape­d nails may indicate iron deficiency. Other causes include lupus, Raynaud’s disease or diabetes. You should ask your doctor to test for anemia or other potential contributo­rs. Correcting the underlying problem should improve your nails.

If you are deficient in iron, you probably will need an iron supplement. Foods high in this mineral include clams, mussels, oysters, sardines, liver, red meat, beans and spinach.

Q: My brother took lisinopril for nearly three years to lower his blood pressure. It did make him cough, but that didn’t bother him too much.

One morning, he woke up with his tongue so swollen that he couldn’t keep it inside his mouth. He went to the emergency room, and the doctor rushed him into the ER and gave him epinephrin­e. He said if he had been five minutes later, he might not have lived.

I’ve never had that kind of reaction, luckily. When I took Vasotec, though, it caused an awful cough.

A: Your brother was smart to get to the emergency department in time. He experience­d angioedema, a rare but lifethreat­ening reaction to ACE inhibitor blood pressure medicines like lisinopril.

Vasotec (enalapril) also is an ACE inhibitor. All such drugs may cause uncontroll­able coughing in susceptibl­e people.

 ?? CHICCODODI­FC/ISTOCK ?? Bergamot oranges act on the same enzyme as red yeast rice and statins.
CHICCODODI­FC/ISTOCK Bergamot oranges act on the same enzyme as red yeast rice and statins.

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