Pittsburgh Post-Gazette

Innovation, cont.

The new UPMC/Pitt research center is a big step

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Pittsburgh’s tradition of innovation will be honored and extended in a big way with the developmen­t of the UPMC Immune Transplant and Therapy Center in an old Ford garage in Bloomfield. A partnershi­p of UPMC and the University of Pittsburgh, the center will research, produce and speed to market drugs that manipulate the immune system to treat disease. The potential — social and economic — is significan­t.

UPMC will invest $200 million to develop the center at 5000 Baum Blvd. The center will take an unusually broad role in drug developmen­t — funding early clinical trials often covered by third parties — with the aim of getting treatments to patients more quickly. Right now, the gap between researchin­g a drug and getting it to patients is so wide that it’s called the “valley of death.”

Bridging the valley would give the center a unique niche in the health care industry and give it the opportunit­y to commercial­ize breakthrou­ghs through UPMC and partnershi­ps with other entities. But that lab-to-bedside approach is just one of the ways in which the UPMC/Pittprojec­t stands out.

Immunother­apy is a cutting-edge field in which some of the nation’s leading health providers — including Johns Hopkins Medicine in Baltimore, Memorial Sloan Kettering Cancer Center in New York and the Cleveland Clinic — are blazing trails. Much of that work is in cancer research. The center here also will focus on organ transplant­s and chronic diseases, especially those related to aging — a boon for the region’s graying population. The center could make Pittsburgh a destinatio­n for immunother­apy, something now claimed largely by medical complexes on the coasts, while giving homegrown ideas a better-than-average shot of success.

Besides enhancing their profiles and altering the dynamics of health care, UPMC and Pitt have the opportunit­y to influence the next wave of innovation in a region long known for breaking ground in health care and otherfield­s. The center envisions sharing its building with other forwardloo­king research ventures and helping to anchor an innovation district for high-tech fields, including the life sciences. Its work will attract other firms andventure capital to support them.

A study last year by the Brookings Institutio­n suggested that Pittsburgh in some ways remains a sleeping giant. It cited a pressing need for the city to better connect research and industry, particular­ly in the life sciences; to create a better environmen­t for entreprene­urs; and to grow the university- and hospital-centered innovation culture. InnovatePG­H, a public-private partnershi­p, was establishe­dto pursue those goals.

UPMC announced plans in November to spend $2 billion building three new specialty hospitals — to be attached to existing facilities — to expand its capacity for cancer, vision, heart and transplant care. The Immune Transplant and Therapy Center is a different kind of animal, one with the potential to transform both health care and the health care industry. It will be a fitting addition to the city and, as Pitt Chancellor Patrick Gallagher said, offer insight into some of medicine’s most challengin­g mysteries.

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