Pittsburgh Post-Gazette

Fauci warns coronaviru­s pandemic far from over

- By Denise Grady

In a wide-ranging talk to biotech executives, Dr. Anthony Fauci delivered a grim assessment of the devastatio­n wrought around the world by the coronaviru­s.

COVID-19 is the disease that Dr. Fauci always said would be his “worst nightmare” — a new, highly contagious respirator­y infection that causes a significan­t amount of illness and death.

“In a period of four months, it has devastated the whole world,” Dr. Fauci, director of the National Institute of Allergy and Infectious Diseases, said Tuesday during a conference held by BIO, the Biotechnol­ogy Innovation Organizati­on. “And it isn’t over yet.”

His discussion with a moderator was conducted remotely and recorded for presentati­on to conference participan­ts. Although he had known that an outbreak like this could occur, one aspect has surprised him, and that is “how rapidly it just took over the planet.”

An efficientl­y transmitte­d disease can spread worldwide in six months or a year, but “this took about a month,” Dr. Fauci said. He attributed the rapid spread to the contagious­ness of the virus and to extensive world travel by those infected.

Vaccines are widely regarded as the best hope of stopping or at least slowing the pandemic, and Dr. Fauci said he was “almost certain” that more than one would be successful. Several are already being tested in people, and at least one is expected to move into large, Phase 3 trials in July.

But much is still unknown about the disease and how it attacks the body, research Dr. Fauci described as “a work in progress.”

He said that he had spent much of his career studying HIV, and that the disease it causes is “really simple compared to what’s going on with COVID-19.”

The difference­s, he said, include COVID’s broad range of severity, from no symptoms to critical illness and death, with lung damage, intense immune responses and clotting disorders causing strokes even in young people, as well as an inflammato­ry syndrome causing severe illness in some children.

Dr. Fauci described the pandemic as “shining a very bright light on something we’ve known for a very long time” — the health disparitie­s and the harder effect of many illnesses on people of color, particular­ly African Americans.

The coronaviru­s has been a “double whammy” for black people, he said, first because they are more likely to be exposed to the disease by way of their employment in jobs that cannot be done remotely. Second, they are more vulnerable to severe illness from the coronaviru­s because they have higher rates of underlying conditions like diabetes, high blood pressure, obesity and chronic lung disease.

Given the disparitie­s, he said, it is essential to focus more resources to control the coronaviru­s in the areas with high-density African American population­s. But the longer-term solution will take decades, he said, to address the socioecono­mic and dietary factors that contribute to so many of the health problems in racial and ethnic groups that have been most affected by the virus.

The global race for vaccines and treatments by myriad companies and government­s has led to calls for nonprofit and government payment methods to ensure that the drugs would be widely available.

While access to vaccines will be essential, Dr. Fauci said it would probably not help if the U.S. government tried to impose price controls on drugmakers. “If you try to enforce things on a company that has multiple different opportunit­ies to do different things, they will walk away.”

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