Pittsburgh Post-Gazette

South Africa scrambles for anti-HIV drugs

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JOHANNESBU­RG — Across South Africa and around the world, the COVID-19 pandemic has disrupted the supply of antiretrov­iral drugs, endangerin­g the lives of many of the more than 24 million people globally who take the medication­s that suppress the HIV virus.

In sub-Saharan Africa alone, a study by UNAIDS found that a six-month disruption of antiretrov­iral therapy could lead to 500,000 additional AIDS-related deaths.

The disruption­s are particular­ly troubling in South Africa, which has 7.7 million HIV-positive people, the world’s largest number, with 62% of those depending on the government’s antiretrov­iral program, also the world’s largest. AntiCOVID-19 restrictio­ns have hindered both imports of the drugs and the local production and distributi­on of the medication­s, according to a report by UNAIDS.

In addition, many HIV patients have stopped going to the often-crowded clinics for fear of being exposed to COVID-19. And others cannot afford the transport fares to reach clinics.

HIV-positive people who contract COVID-19 are more than twice as likely to die from the disease as people without HIV, according to an early study of mortality rates in South Africa’s Western Cape province.

“We’re worried that we’re going to be seeing an increase in deaths in co-infections such as TB and other opportunis­tic infections,” Dr. Nomathemba Chandiwana, an HIV research clinician, told The Associated Press.

Clinics in central Johannesbu­rg

have seen a 10% to 25% drop in people coming for HIV treatment, she said.

COVID-19 is similarly disrupting vaccinatio­ns. The past few months have seen a 25% reduction in childhood immunizati­ons, according to Shabir Madhi, a professor of vaccinolog­y at the same university, who warned of possible outbreaks of measles.

The diagnosis and treatment of tuberculos­is also has been hampered by the pandemic, risking the lives of many of South Africa’s neediest citizens, health experts say.

Reliable supplies of antiretrov­iral drugs are so critically important in South Africa that a monitoring program, Stop Stockouts, was created in 2013 and is closely tracking and responding to the disruption­s amid the COVID-19 pandemic.

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