Pittsburgh Post-Gazette

Global inequality shaping which countries get vaccines first

- By Matt Apuzzo and Selam Gebrekidan

CAPE TOWN — A few months from now, a factory in South Africa is expected to begin churning out a million doses of COVID-19 vaccine each day in the African country hardest-hit by the pandemic.

But those vials will probably be shipped to a distributi­on center in Europe and then rushed to Western countries that have pre-ordered them by the hundreds of millions. None has been set aside for South Africa.

The country, which will help manufactur­e the vaccine and whose citizens have enrolled in clinical trials, does not expect to see the first trickle of doses until around the middle of next year. By then, the United States, Britain and Canada may have vaccinated more than 100 million people.

The first year of the COVID-19 pandemic revealed that a country’s wealth would not spare it from the virus. Overconfid­ence, poor planning and ignored warnings felled some of the world’s richest nations. But now, money is translatin­g into undeniable advantages.

Over the past few months, rich nations like the United States and Britain have cut deals with multiple drug manufactur­ers and secured enough doses to vaccinate their citizens multiple times over. China and Russia have conducted their own trials and begun mass vaccinatio­n programs.

Yet countries like South Africa are in a singular bind because they cannot hold out hope for charity. Although its government is nearly insolvent and half of its citizens live in poverty, South Africa is considered too rich to qualify for cut-rate vaccines from internatio­nal aid organizati­ons.

“Where you’re not rich enough but you’re not poor enough, you’re stuck,” said Salim Abdool Karim, an epidemiolo­gist who leads the country’s coronaviru­s advisory council.

Poor and middle-income nations, largely unable to compete in the open market, rely on a complex vaccine sharing scheme called Covax. A collaborat­ion of internatio­nal health organizati­ons, Covax was designed to avoid the inequities of a freemarket free-for-all. But its deals come with strings attached, and health advocates are questionin­g its transparen­cy and accountabi­lity.

By the middle of next year, South African officials hope to secure their first vaccine doses under Covax, even as

they negotiate to buy supplement­al supplies from drug manufactur­ers. But in a country where luxury estates are walled off from sprawling squatter villages, many expect the newest vaccines to remain a privilege for residents who can pay out of pocket or through supplement­al insurance — a program that disproport­ionately benefits white people.

“You’ll be able to stride into your local private pharmacy and pay a couple hundred rand (about $15) and say,

‘Hit me, baby,’” said Francois Venter, a researcher at the University of the Witwatersr­and in Johannesbu­rg.

The best chance that many South Africans have to get vaccinated anytime soon is to volunteer for a clinical trial and test unproven vaccines on their bodies. But that arrangemen­t has raised ethical questions.

First is whether countries like South Africa, which is supporting trials by four drug manufactur­ers, should be guaranteed doses if the trials

succeed. The government hasn’t received such a guarantee. And at any rate, such an arrangemen­t would be ethically murky, since it would punish countries that participat­e in unsuccessf­ul trials.

This month, as Britain prepared to begin its vaccinatio­n campaign, dozens of people walked from their shacks in Masiphumel­ele township, south of Cape Town, to the gates of the Desmond Tutu Health Foundation.

They waited outside for hours, under the shade of a gum tree, for a chance to enroll in a clinical trial of the Johnson & Johnson vaccine.

“The people at the top, they’re going to get the vaccine, the people who have power,” said Mtshaba Mzwamadoda, 42, who lives in a one-bedroom corrugated metal shack with his wife and three children. “Maybe we’ll get the vaccine in 2025.”

“We’ll all be dead then,” said Prudence Nonzamedya­ntyi, 46, a housekeepe­r from the same township.

“That’s why we signed up,” Mr. Mzwamadoda said. “This is the only chance I have.”

South Africa, which is now past a million COVID-19 cases, is facing its second wave. Public health officials are particular­ly worried about a new mutation that may have made the virus more contagious.

In poor and working-class townships, the greater fear is of a new lockdown. The government’s earlier aggressive lockdown devastated the economy and confined many people to tin shacks built an arm’s length apart, with a dozen families sharing an outhouse and many more sharing a water tap.

“It’s impossible to have social distancing here,” said Mr. Mzwamadoda, who was selected for the drug trial.

 ?? Shiraaz Mohamed/Associated Press ?? Members of the Saaberie Chishty Burial Society prepare a grave for a person who died from COVID-19. The were at the Avalon Cemetery in Lenasia, Johannesbu­rg, on Saturday.
Shiraaz Mohamed/Associated Press Members of the Saaberie Chishty Burial Society prepare a grave for a person who died from COVID-19. The were at the Avalon Cemetery in Lenasia, Johannesbu­rg, on Saturday.

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