Pittsburgh Post-Gazette

Book captures fight to save children from fatal illnesses

- By Lorraine Starsky

The COVID-19 pandemic has revived public discussion about vaccines. In her book, “A Good Time to Be Born: How Science and Public Health Gave Children a Future,” pediatrici­an Dr. Perri Klass examines the historic strides in public health and medical science that led to the developmen­t of vaccines, as well as antibiotic­s, which allow today’s parents the blissful expectatio­n that their children will thrive and survive them. Just 100 years ago, parents lived with the routine dreaded possibilit­y that at least one, if not more, of their children would die in infancy or childhood.

Stillbirth­s, birth traumas, neonatal tetanus, smallpox, typhoid, contaminat­ed milk, pertussis (whooping cough), diphtheria, tuberculos­is, scarlet fever, meningitis, polio, wound infections and more contribute­d to high death rates of infants and children in previous centuries. Although many of these deadly disorders were exacerbate­d by poverty, crowding and inferior hygienic conditions, Dr. Klass documents that the wealthy also lost children to these ailments.

The author juxtaposes the publicly acknowledg­ed grief surroundin­g the deaths of white children to the brutal conditions faced by enslaved mothers and their children. Although many white children’s deaths do not appear in official records, the offspring of enslaved women were carefully accounted for because they were property. Dr. Klass cites the work of economist Richard Steckel, who studied the data kept by slave owners. In scrutinizi­ng these records, Steckel concluded that the mortality rates of enslaved infants and children were twice what was found in the U.S. population of that time.

According to estimates, up to 30% of infants died before reaching the age of 1 in some U.S. cities in 1900. Addressing this challenge required the collection of accurate data. Without infant and child mortality statistics, it was impossible to craft effective responses. Trailblaze­rs such as Dr. S. Josephine Baker and Dr. Esther Pohl Lovejoy worked diligently to study and treat babies and young children and recorded their interventi­ons, thus establishi­ng mothers, infants and children as a key focus of public health.

Births were generally not officially registered in the United States until well into the 20th century, which impeded collection of infant and child mortality data. The fight against child labor, the campaign for compulsory public education and mounting public health efforts devoted to reducing infant and child mortality all merged into legislatio­n that mandated birth registrati­ons.

The end of the 19th century and the early decades of the 20th century brought microbiolo­gical understand­ing of infectious diseases. Medicine was now poised on the exciting precipice of effective prevention and treatment. Dr. Klass details the heartbreak of Dr. Mary

Putnam Jacobi and Dr. Abraham Jacobi, the power couple of the emerging specialty of pediatrics who lost their 7-year-old son to diphtheria in 1883. By 1895, diphtheria antitoxin was in production, reducing the number of children lost to this vicious disease that blocked their throats and choked them to death.

In 1921, a vaccine against diphtheria was formulated that was superior to the antitoxin. The post-World War II era saw the licensing of a vaccine that protected against diphtheria, pertussis (whooping cough) and tetanus. Dr. Klass notes that baby boomers were the first generation to benefit from this vaccine, followed by the dramatic developmen­t of the polio vaccine that ended frightenin­g polio outbreaks. More vaccines against other childhood diseases followed.

Dr. Klass points to continuing racial inequaliti­es in infant and maternal mortality. Certain groups still do not share equally in the stunning bounty of progress produced by scientific medical advances and public health innovation­s. Programs such as Healthy Start, Nurse Family Partnershi­p and WIC (Special Supplement­al Nutrition Program for Women, Infant and Children) have made contributi­ons to addressing disparitie­s, but they are not mentioned in this book.

Nonetheles­s, Dr. Klass has done an extraordin­ary job of telling the poignant stories of parents, some poor and some affluent, who faced the devastatin­g loss of young lives and the powerful stories of relentless medical pioneers and public health trailblaze­rs who battled preventabl­e infant and child deaths. She is a gifted writer who has produced history that reads like a novel.

 ?? W.W. Norton & Company ?? ‘A GOOD TIME TO BE BORN’ By Perri Klass W.W. Norton & Company ($28.95)
W.W. Norton & Company ‘A GOOD TIME TO BE BORN’ By Perri Klass W.W. Norton & Company ($28.95)

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