Pittsburgh Post-Gazette

Scientists: More variants inevitable

- By Laura Ungar

Get ready to learn more Greek letters. Scientists warn that omicron’s whirlwind advance practicall­y ensures it won’t be the last version of the coronaviru­s to worry the world.

Every infection provides a chance for the virus to mutate, and omicron has an edge over its predecesso­rs: It spreads way faster despite emerging on a planet with a stronger patchwork of immunity from vaccines and prior illness.

That means there are more people in whom the virus can further evolve. Experts don’t know what the next variants will look like or how they might shape the pandemic, but they say there’s no guarantee the sequels of omicron will cause milder illness or that existing vaccines will work against them.

They urge wider vaccinatio­n now, while today’s shots still work.

“The faster omicron spreads, the more opportunit­ies there are for mutation, potentiall­y leading to more variants,” said Leonardo Martinez, an infectious disease epidemiolo­gist at Boston University.

Since it emerged in midNovembe­r, omicron has raced across the globe like fire through dry grass. Research shows the variant is at least twice as contagious as delta and at least four times as contagious as the original version of the virus.

Omicron is more likely than delta to re-infect individual­s who previously had COVID-19 and to cause “breakthrou­gh infections” in vaccinated people while also attacking the unvaccinat­ed. The World Health Organizati­on reported a record 15 million new COVID-19 cases for the week of Jan. 3-9, a 55% increase from the previous week.

Along with keeping comparativ­ely healthy people out of work and school, the ease with which the variant spreads increases the odds the virus will infect and linger inside people with weakened immune systems — giving it more time to develop potent mutations.

“It’s the longer, persistent infections that seem to be the most likely breeding grounds for new variants,” said Dr. Stuart Campbell Ray, an infectious disease expert at Johns Hopkins University. “It’s only when you have very widespread infection that you’re going to provide the opportunit­y for that to occur.”

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