Analysis indicates 2 strains of virus

Monkeypox cases hit 20 in the U.S.

NEWYORK — Genetic analysis of recent monkeypox cases suggests there are two distinct strains in the U.S., health officials said Friday, raising the possibility that the virus has been circulating undetected for some time.

Meanwhile, the number of U.S. cases of monkeypox rose to 20, six more than late last week, as the government began shipping drugs and vaccines to eight states that requested them.

All the U.S. cases of the disease, seen in 11 states, are recovering or have already recovered, officials from the Centers for Disease Control and Prevention said Friday in a briefing.The government has delivered 1,200 doses of vaccine and 100 courses of treatment, they said.

Many of the U.S. cases were caused by the same strain as recent cases in Europe, but a few samples show a different strain, federal health officials said. Each strain had been seen in U.S. cases last year, before the recent international outbreak was identified.

Analysis from many more patients will be needed to determine how long monkeypox has been circulating in the U.S. and elsewhere, said Jennifer McQuiston of the Centers for Disease Control and Prevention.

“I think it’s certainly possible that there could have been monkeypox cases in the United States that went under the radar previously, but not to any great degree,” she told reporters Friday. However, she added, “there could be community level transmission that is happening” in parts of U.S. where the virus has not yet been identified.

The CDC said it is trying to increase its work on finding infections, and it’s likely more cases will be reported.

The findings mean the outbreak likely will be difficult to contain, said Dr. Angela Rasmussen, a virologist at the University of Saskatchewan.

It’s not clear how long infections have been happening, and where. Some infections may have been misdiagnosed as something else.

“We don’t really have a good sense of how many cases there are out there,” Dr. Rasmussen said.

Monkeypoxis endemic in parts of Africa, where people have been infected through bites from rodents or small animals. It does not usually spread easily among people.

But last month, cases began emerging in Europe and the United States. Many — but not all — of those who contracted the virus had traveled internationally, and health officials in a growing number of countries are investigating.

Hundreds of other cases have been found in other countries, many apparently tied to sexual activity at two recent raves in Europe.

So far, many of the reported cases outside Africa have been in men who have sex with men, but health officials stress that anyone can get monkeypox.

The illness typically begins with flu-like symptoms and swelling of the lymph nodes, followed by a rash on the face and body.