San Antonio Express-News

SCREENING THOSE ‘SILENT SPREADERS’

Nonprofit is aiming to test people with no virus symptoms

- By Lauren Caruba STAFF WRITER

After Graham Weston caught the coronaviru­s from his son, who hadn’t shown any symptoms, the San Antonio tech entreprene­ur realized that the role of “silent spreaders” demanded more attention.

He and other prominent philanthro­pic leaders in the city formed a new nonprofit with the express purpose of screening hundreds and eventually thousands of people to identify who is infected and asymptomat­ic and keep them from unknowingl­y spreading the virus.

The larger goal is even more ambitious: deliver an effective way of supporting society’s recovery from the pandemic.

“We can never really suppress the virus and give people the confidence to go back (to school or work) when we have silent spreaders walking through our population,” said Weston, founder of the 80 | 20 Foundation and former CEO and chairman of Rackspace Technology.

The nonprofit, called Community Labs, has adopted a new approach to testing that focuses on micro population­s in shared places, such as area schools and businesses.

It is using an existing test developed by Thermo Fisher Scientific. The polymerase chain reaction, or PCR, test relies on a sample taken from the front of the nostril — easier on the person getting tested. Results will be available within 24 hours, far

faster than many providers of coronaviru­s tests, the nonprofit’s leaders said Thursday during their announceme­nt of the initiative.

The nonprofit will pilot the testing effort in the Somerset Independen­t School District. It has the capacity to process 600 tests a day and aims to scale up to 12,000 tests a day by November, with the goal of lowering the price to $35 per test.

Community Labs is working with Biobridge Global, which houses the nonprofit and conducts the testing in collaborat­ion with UT Health San Antonio. Biobridge, which operates San Antonio’s blood bank, owns its own lab off Interstate 10 near Vance Jackson on the West Side.

Experts estimate that up to half of people who contract the coronaviru­s may display no symptoms, said bank executive J. Bruce Bugg Jr., chairman and trustee of the Tobin Endowment and co-founder of Community Labs. While hospitals have widely screened patients for the coronaviru­s when they are scheduled for surgery, federal and local health officials have largely prioritize­d testing people with symptoms.

It’s an approach that has persisted since early in the pandemic, when testing for the coronaviru­s was severely limited by regulatory, processing and supply chain bottleneck­s. Health department­s, including the San Antonio Metropolit­an Health District, initially focused their efforts on people who were severely ill, those with classic symptoms and front-line workers.

Metro Health briefly tested asymptomat­ic people in the community earlier this year but halted the effort when a surge of cases over the summer caused demand for testing to skyrocket.

While testing those with symptoms may help diagnose people with COVID-19, it does little to halt chains of transmissi­on that stem from asymptomat­ic carriers. To fill that testing gap, Community Labs is taking the “exact opposite” approach, Bugg said.

He said the goal is to create a strong testing model that screens for asymptomat­ic carriers and that can be replicated and applied in cities across the state.

Community Labs’ approach hinges on quick turnaround times, which are not typical with the traditiona­l testing. Waiting a week for results would render the value of testing asymptomat­ic people moot, Weston said, as they won’t know to isolate themselves and already could have spread the virus to others by the time they learn they are infected.

Dr. Rachel Beddard, chief medical officer of Biobridge, said the company already conducts fast, highvolume testing for communicab­le diseases on blood products collected by the South Texas Blood and Tissue Center and on the tissue, bone marrow and stem cells gathered by Gencure, another subsidiary.

Earlier this year, federal regulators granted an emergency use authorizat­ion for the coronaviru­s test that Biobridge is using.

Somerset ISD, a seven school system in rural Southwest Bexar County, was selected as a demonstrat­ion site after its superinten­dent, Saul Hinojosa, agreed to participat­e.

With about 40 percent of all students having returned to school for in-person learning, the district will begin testing students and staff Wednesday, starting with students involved in extracurri­cular activities, all high school staff and all nurses and police officers. Only students whose parents sign a consent form will be tested at school, Hinojosa said.

The goal is to test as many students as possible so they, their parents and staff feel comfortabl­e returning to school. If everything goes according to plan and enough students agree to get tested, Hinojosa said, the entire district could be back learning face-to-face earlier than expected.

“We need students in the classroom because that’s where they learn best, and we hope that this strategy will lessen the concern on parents, along with the anxiety, to where they feel confident that the school campus is a safe environmen­t for the kids,” he said.

Unlike the deep nasal swabs that have been used to collect samples for many coronaviru­s tests, the test used by Community Labs uses a sample that’s simpler and far less invasive to collect. Participan­ts rub a small Q-tip inside each nostril for five seconds before dropping it into a test tube.

Community Labs was cofounded by Weston, Bugg and J. Tullos Wells, managing director of the Kronkosky Charitable Foundation. Weston is serving as chairman, while Bugg and Wells are vice chairmen.

The Kronkosky and 80 | 20 foundation­s and the Tobin Endowment have contribute­d a combined $2.5 million to start the nonprofit.

“We can never really suppress the virus and give people the confidence to go back (to school or work) when we have silent spreaders walking through our population.”

Graham Weston, chairman of Community Labs

 ?? Photos by Bob Owen / Staff photograph­er ?? Graham Weston, right, chairman of new nonprofit Community Labs, bumps elbows with J. Bruce Bugg Jr., the nonprofit’s vice chairman, at a news conference.
Photos by Bob Owen / Staff photograph­er Graham Weston, right, chairman of new nonprofit Community Labs, bumps elbows with J. Bruce Bugg Jr., the nonprofit’s vice chairman, at a news conference.
 ??  ?? Alejandro Trevino prepares instrument­s to be used in the Quant Studio 7 Flex testing machines near him.
Alejandro Trevino prepares instrument­s to be used in the Quant Studio 7 Flex testing machines near him.
 ?? Bob Owen / Staff photograph­er ?? J. Bruce Bugg Jr., a vice chairman of Community Labs, said the nonprofit aims to create a strong testing model that screens for asymptomat­ic carriers and that can be replicated and applied in cities across the state.
J. Tullos Wells is a vice chairman of Community Labs.
Bob Owen / Staff photograph­er J. Bruce Bugg Jr., a vice chairman of Community Labs, said the nonprofit aims to create a strong testing model that screens for asymptomat­ic carriers and that can be replicated and applied in cities across the state. J. Tullos Wells is a vice chairman of Community Labs.
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