San Diego Union-Tribune (Sunday)

SCIENTISTS EYE ROLE OF AEROSOLS IN CORONAVIRU­S TRANSMISSI­ON

Tiny particles may pose big problem, but risk is uncertain

- BY MALCOLM RITTER Ritter writes for The Associated Press.

At a University of Maryland lab, people infected with the novel coronaviru­s take turns sitting in a chair and putting their faces into the big end of a large cone. They recite the alphabet and sing or just sit quietly for a half hour. Sometimes they cough.

The cone sucks up everything that comes out of their mouths and noses. It’s part of a device called “Gesundheit II” that is helping scientists study a big question: Just how does the virus that causes COVID-19 spread from one person to another?

It clearly hitchhikes on small liquid particles sprayed out by an infected person. People expel particles while coughing, sneezing, singing, shouting, talking and even breathing. But the drops come in a wide range of sizes, and scientists are trying to pin down how risky the various kinds are.

The answer affects what we should all be doing to avoid getting sick. That’s why it was thrust into headlines a few days ago when a U.S. health agency appeared to have shifted its position on the issue, but later said it had published new language in error.

The recommenda­tion to stay at least 6 feet apart — some authoritie­s cite about half that distance — is based on the idea that larger particles fall to the ground before they can travel very far. They are like the droplets in a spritz of a window cleaner, and they can infect somebody by landing on their nose, mouth or eyes, or maybe being inhaled.

But some scientists are now focusing on tinier particles, the ones that spread more like cigarette smoke. Those are carried by wisps of air and even upward drafts caused by the warmth of our bodies. They can linger in the air for minutes to hours, spreading throughout a room and build up if ventilatio­n is poor.

The potential risk comes from inhaling them. Measles can spread this way, but the new coronaviru­s is far less contagious than that.

For these particles, called aerosols, “6 feet is not a magic distance,” says Linsey Marr, a leading researcher who is studying them at Virginia Tech in Blacksburg. But she says it’s still important to keep one’s distance from others, “the farther the better,” because aerosols are most concentrat­ed near a source and pose a bigger risk at close range.

Public health agencies have generally focused on the larger particles for coronaviru­s. That prompted more than 200 other scientists to publish a plea in July to pay attention to the potential risk from aerosols.

The issue drew attention recently when the U.S. Centers for Disease Control and Prevention posted and then deleted statements on its website that highlighte­d the idea of aerosol spread. The agency said the posting was an error, and that the statements were just a draft of proposed changes to its recommenda­tions.

Dr. Jay Butler, CDC’S deputy director for infectious disease, told The Associated Press that the agency continues to believe larger and heavier droplets that come from coughing or sneezing are the primary means of transmissi­on.

Last month Butler told a scientific meeting that current research suggests aerosol spreading of the coronaviru­s is possible but it doesn’t seem to be the main way that people get infected. Further research may change that conclusion, he added, and he urged scientists to study how often aerosol spread of the coronaviru­s occurs, what situations make it more likely and what reasonable steps might prevent it.

Marr said she thinks infection by aerosols is “happening a lot more than people initially were willing to think.”

As a key piece of evidence, Marr and others point to socalled “supersprea­der” events where one infected person evidently passed the virus to many others in a single setting.

In March, for example, after a choir member with coronaviru­s symptoms attended a rehearsal in Washington state, 52 others who had been seated throughout the room were found to be infected and two died. In a crowded and poorly ventilated restaurant in China in January, the virus evidently spread from a lunchtime patron to five people at two adjoining tables in a pattern suggesting aerosols were spread by the air conditione­r. Also in January, a passenger on a Chinese bus apparently infected 23 others, many of whom were scattered around the vehicle.

Butler said such events raise concern about aerosol spread but don’t prove it happens.

Scientists who warn about aerosols say current recommenda­tions still make sense.

Wearing a mask is still important, and make sure it fits snugly. Keep washing those hands diligently. And again, staying farther apart is better than being closer together. Avoid crowds, especially indoors.

 ?? AP ?? The Gesundheit II machine is used to study how virus particles spread.
AP The Gesundheit II machine is used to study how virus particles spread.

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