San Diego Union-Tribune (Sunday)

UCSD: WASTEWATER TESTS DETECT HIGHER LEVELS OF VIRUS; SURGE LIKELY

- BY JONATHAN WOSEN

If our toilets are any indication, San Diego County may be in for a sharp spike in coronaviru­s cases soon.

On Saturday, UC San Diego officials warned that samples from the Point Loma Wastewater Treatment Plant, which processes flushed waste from two out of every three San Diegans, has the highest levels of the coronaviru­s that the university has seen since February. Both the Delta and Omicron variants of the virus are fueling this rise.

Researcher­s have consistent­ly found that when viral levels go up in wastewater, cases usually increase within a couple weeks, putting the region on track for a sizeable surge around the start of 2022. And that has scientists and public health officials again urging the unvaccinat­ed to get vaccinated, the immunized to return for boosters, and everyone to think hard before attending large and unmasked indoor gatherings.

“There will be an unpreceden­ted surge in COVID cases in San Diego. That is already in motion,” said Rob Knight, a microbiome expert and one of the leaders of UCSD’S wastewater surveillan­ce effort. “There’s still an opportunit­y to keep this in the wastewater and out of the hospitals and out of the morgue.”

The surprise weekend announceme­nt was the culminatio­n of a short, intense scramble by the university. Around 4:30 p.m. Friday, Knight got a text message from a member of his team reporting the sharp increase. The university’s COVID-19 monitoring team then hustled to make sense of the data. Their main question: Was Omicron driving the uptick? It would have taken at least a week to come up with an answer via genetic sequencing. So instead, researcher­s worked late into the night and Saturday morning to run a molecular test specifical­ly designed to distinguis­h variants. That test revealed that both the Delta and

Omicron variants were contributi­ng to the rise.

“It’s like you have two pandemics going on at once, with different strains of the virus,” Knight said.

Wastewater testing works because although COVID-19 is best known for its attack on the airways, the virus also slips inside the cells lining the intestines and can be shed through a person’s stool before they feel sick. Local data throughout the past year show that leaps in wastewater viral levels presage infections spotted by standard nose and throat swabs.

UCSD’S announceme­nt included a statement from Dr. Wilma

Wooten, the county’s public health officer, noting that the new findings confirm growing evidence that Omicron is spreading. And Dr. Christophe­r Longhurst, chief medical officer of UCSD Health, pleaded with the public to get tested early and often for the virus.

“If you feel the slightest symptoms, if you think you might have had contact with someone with COVID-19, if you’ve gathered in crowds without masks, if you’re planning a get-together — test, test, test,” he said in a statement. “Don’t wait.”

jonathan.wosen @sduniontri­bune.com

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