San Diego Union-Tribune

VACCINE TESTERS RECRUIT THOUSANDS

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You may be wondering: How can I volunteer for a COVID-19 vaccine study?

Government­s and companies are setting up websites where people can sign up.

Enthusiasm is high: More than 400,000 people have signed a registry of possible volunteers that’s part of a vaccine network set up by the U.S. National Institutes of Health.

But before raising your hand, it’s important to understand how the research works.

Initial studies include only a few dozen young, healthy volunteers, since this is the first chance to see if a shot causes a risky reaction in people. Older adults, anyone with a serious underlying illness, and pregnant women are typically excluded from this testing stage.

Midstage studies of

COVID-19 vaccines recruit a few hundred people, including some older adults. The focus is on comparing how people’s immune systems react to different doses, as well as getting more safety data.

In final-stage studies, scientists need tens of thousands of volunteers who ref lect the diversity of the population, including those at high risk of severe illness from the virus. So volunteers can include people who are older than 65 and people with chronic health problems such as diabetes.

Enough study participan­ts have to be exposed to the virus for researcher­s to be able to tell if the vaccine works. That’s why essential workers, such as grocery or transporta­tion workers who come into frequent contact with others, are especially sought after for the last testing phase. It’s also why researcher­s are recruiting in places where the virus is spreading, not areas that have it under control — so even if you meet the eligibilit­y criteria, you might not be called back, depending on where you live.

Volunteers won’t know if they’re getting the vaccine or a dummy shot.

The World Health Organizati­on counts 10 vaccines worldwide in this final stage of testing, and dozens more are in earlier stages. A few websites list vaccine studies for people interested in volunteeri­ng.

• The website clinicaltr­ials.gov lets people search for COVID-19 vaccine studies by country.

Many regions, such as the European Union, also have their own research registries.

• And if local hospitals, clinics or testing labs in your area are looking for volunteers, you’ll likely see advertisem­ents or f lyers with a number to call for informatio­n.

 ?? PETER HAMLIN AP ??
PETER HAMLIN AP

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