San Diego Union-Tribune

U.K. STOCKING UP ON VACCINE DOSES

Hopes to get OK to start inoculatio­n drives within days

- BY JILL LAWLESS Lawless writes for The Associated Press.

LONDON

Britain said Sunday it has secured 2 million more doses of a promising coronaviru­s vaccine as it gears up to launch within days the country’s most ambitious inoculatio­n program in decades.

The U.K. has had Europe’s deadliest coronaviru­s outbreak, with more than 58,000 confirmed virus-related deaths. It now hopes to hit a more positive milestone by becoming one of the first countries in the world to start vaccinatin­g its population against COVID-19.

The U.K. government has agreed to buy more than 350 million doses of vaccines from seven different producers, should they prove effective, as it prepares to vaccinate as many of the country’s 67 million people as possible.

The Department of Health said Sunday it had increased its order for a vaccine developed by U.S. firm Moderna from 5 million to 7 million doses, enough for 3.5 million people.

The Moderna vaccine is expected to be referred soon to the U.K.’s Medicines and Healthcare Products Regulatory Agency, to see if it is safe and effective. Two other vaccines — one developed by Pfizer and German firm BioNTech, the other by Oxford University and AstraZenec­a — are already being assessed by the regulator, the final stage before being rolled out.

Britain has ordered 40 million doses of the Pfizer/ BioNTech vaccine and 100 million doses of the Oxford/ AstraZenec­a vaccine.

Hospitals in England have been told they could receive the first doses of the Pfizer shot as early as the week of Dec. 7 if it receives approval, the Guardian and Financial Times reported.

The U.S. vaccinatio­n program also hopes to begin inoculatin­g some Americans in December.

The government says frontline health care workers and nursing home residents will be the first to be vaccinated, followed by older people, starting with those over 80. The plan is to work down the age and risk groups until everyone 18 and older has been inoculated.

Non-medical staff, including volunteer f irstaiders, are already being trained to give the shots, which will be administer­ed at around 1,000 community vaccinatio­n centers and 40 to 50 large-scale facilities in stadiums and conference venues, according to a government planning document.

Prime Minister Boris Johnson said officials hope to vaccinate “the vast majority of the people who need the most protection by Easter.”

Writing in the Mail on Sunday, Johnson said the rollout of a vaccine could be “just days away.” But he said there would not be a quick end to the onerous restrictio­ns on business and everyday life that have been imposed to curb the spread of the virus.

“There are still long weeks and months ahead before we can be completely confident that we can vaccinate enough people in the country, and thereby remove enough targets for the

virus, in order to beat the disease,” he wrote.

A four-week national lockdown in England is due to end Wednesday and will be replaced by a three-tiered system of regional measures. The vast majority of the country is being put into the upper two tiers, meaning most people will be barred from meeting up with friends indoors, pubs and restaurant­s still face restrictio­ns and everything from large weddings to choir practices are being banned.

Pfizer and BioNTech say their vaccine is 95 percent effective, according to preliminar­y data. It must be stored at ultra-cold temperatur­es of around minus 70 degrees Celsius (minus 94 Fahrenheit). The Moderna vaccine, which also needs to be stored at freezer temperatur­es, was also about 95 percent effective in clinical trials, the company said.

The Oxford-AstraZenec­a vaccine can be stored at convention­al refrigerat­or temperatur­es, making its distributi­on much simpler, and is also cheaper than its main rivals. But some scientists have questioned gaps in its reported results.

Oxford and AstraZenec­a reported last week that their vaccine appeared to be 62 percent effective in people who received two doses, and 90 percent effective when volunteers were given a half dose followed by a full dose. They said the half dose was administer­ed because of a manufactur­ing error, and they plan a new clinical trial to investigat­e the most effective dosing regimen.

 ?? AP FILE ?? The U.K. government says it has committed to purchase 350 million coronaviru­s vaccine doses and hopes to soon begin an inoculatio­n program.
AP FILE The U.K. government says it has committed to purchase 350 million coronaviru­s vaccine doses and hopes to soon begin an inoculatio­n program.

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