DOCTORS TRY TO EXPLAIN LINGERING LOSS OF SMELL
Some virus patients are going months without its recovery
The doctor slid a miniature camera into the patient’s right nostril, making her whole nose glow red with its bright miniature light.
“Tickles a bit, eh?” he asked as he rummaged around her nasal passages, the discomfort causing tears to well in her eyes and roll down her cheeks.
The patient, Gabriella Forgione, wasn’t complaining. The 25-year-old pharmacy worker was happy to be prodded and poked at the hospital in Nice, in southern France, to advance her increasingly pressing quest to recover her sense of smell. Along with her sense of taste, it suddenly vanished when she fell ill with COVID-19 in November, and neither has returned.
Being deprived of the pleasures of food and the scents of things that she loves are proving tough on her body and mind. Shorn of odors both good and bad, Forgione is losing weight and self-confidence.
“Sometimes I ask myself, ‘Do I stink?’” she confessed.
“Normally, I wear perfume and like for things to smell nice. Not being able to smell bothers me greatly.”
A year into the coronavirus pandemic, doctors and researchers are still striving to better understand and treat the accompanying epidemic of COVID-19-related anosmia — loss of smell — draining much of the joy of life from an increasing number of sensorially frustrated longerterm sufferers like Forgione.
Even specialist doctors say there is much about the condition they still don’t know and they are learning as they go along in their diagnoses and treatments.
For most people, the olfactory problems are temporary, often improving on their own in weeks. But a small minority are complaining of persistent dysfunction long after other COVID-19 symptoms have disappeared. Some have reported continued total or partial loss of smell six months after infection. The longest, some doctors say, are now approaching a full year.
Researchers working on the vexing disability say they are optimistic that most will eventually recover but fear some will not. Some doctors are concerned that growing numbers of smell-deprived patients, many of them young, could be more prone to depression and other difficulties and weigh on strained health systems.
Losing the sense of smell can be more than a mere inconvenience. Smoke from a spreading fire, a gas leak, or the stink of rotten food can all pass dangerously unnoticed. Fumes from a used diaper, dog’s feces on a shoe or sweaty armpits can be embarrassingly ignored.
The examinations on patients also include language and attention tests. The Nice researchers are exploring whether olfactory complaints are linked to COVIDrelated cognitive difficulties, including problems with concentrating. Patient Evan Cesa stumbled by picking the word “ship” when “kayak” was the obvious choice on one test.
“That is completely unexpected,” said Magali Payne, a speech therapist on the team at the Cote d’Azur University’s CoBTeK lab. “This young man shouldn’t be experiencing linguistic problems.”
“We have to keep digging,” she said. “We are finding things out as we see patients.”