San Diego Union-Tribune

DANISH STUDY: COVID REINFECTIO­NS RARE

Researcher­s say most people protected for 6 months after 1st bout

- BY APOORVA MANDAVILLI Mandavilli writes for The New York Times.

The vast majority of people who recover from COVID-19 remain shielded from the virus for at least six months, researcher­s reported Wednesday in a large study from Denmark.

Prior infection with the coronaviru­s reduced the chances of a second bout by about 80 percent in people younger than 65, but only by about half in those older than 65. But those results, published in the journal Lancet, were tempered by many caveats.

The number of infected older people in the study was small. The researcher­s did not have any informatio­n beyond the test results, so it’s possible that only people who were mildly ill the first time became infected again and that the second infections were symptom-free.

Scientists have said that reinfectio­ns are likely to be asymptomat­ic or mild because the immune system will suppress the virus before it can do much damage. The researcher­s also did not assess the possibilit­y of reinfectio­n with newer variants of the virus.

Still, the study suggests that immunity to a natural infection is unpredicta­ble and uneven, and it underscore­s the importance of vaccinatin­g everyone — especially older people, experts said.

“You can certainly not rely on a past infection as protecting you from being ill again, and possibly quite ill if you are in the elderly segment,” said Steen Ethelberg, an epidemiolo­gist at Statens Serum Institut, largely

Denmark’s public health agency.

Because people older than 65 are at highest risk of severe disease and death, he said, “they are the ones we are most eager to protect.”

Rigorous estimates of second infections have generally been rare because many people worldwide did not initially have access to testing, and laboratori­es require genetic sequences from both rounds of testing to confirm a reinfectio­n.

But the findings are consistent with those from experiment­s in a wide variety of settings: sailors on a fishing trawler in Seattle, Marine Corps recruits in South Carolina, health care workers in Britain and patients at clinics in the United States.

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