San Diego Union-Tribune

RESTORE TAX INCENTIVES FOR LIFE SCIENCES INNOVATION­S

- BY KEVIN MATCHETT is senior director of global product developmen­t at Pfizer’s R&D site in La Jolla. He lives in Pacific Beach.

The response to the COVID-19 pandemic, by some elected officials and citizens alike, has again highlighte­d the dangers of playing politics with science. I am not a politician. The pandemic has showcased the critical role that innovative research and developmen­t play — in La Jolla and across the state — in combating our greatest public health threats. Unfortunat­ely, California policymake­rs may be hampering our ability to respond to this and future pandemics by not making smart investment­s now in our innovation ecosystem.

The researcher­s, scientists and biopharmac­eutical manufactur­ers that are part of California’s life sciences sector are helping lead the global response to the COVID-19 pandemic. We are developing scientific innovation­s to diagnose, treat and mitigate the spread of this potentiall­y deadly virus. To date, the life sciences innovation ecosystem has produced three vaccines, one with full approval by the U.S. Food and Drug Administra­tion and two with emergency use authorizat­ion.

Additional­ly, California’s life sciences industry has contribute­d to more than 389 FDA-approved tests, 10 FDAapprove­d treatments and launched more than 6,225 COVID-19 clinical trials, all while continuing to pursue our work to discover treatments and cures for other diseases.

These scientific innovation­s were a bright spot in an otherwise tumultuous 2020. Their impact will extend far beyond the current pandemic. There are more than 3,700 California-based life sciences companies. In 2019 alone, those companies entered 1,380 medicines into clinical trials and had 696 new medicines in the pipeline to treat cancer, infectious diseases, central nervous system disorders and many others.

The industry is helping to catalyze transforma­tional changes to the health care system, including by addressing diseases that disproport­ionately affect racial and ethnic minorities, improving access to critical medicines and enhancing clinical trial diversity.

In addition to delivering innovative treatments and cures, California’s life sciences industry is also a major jobs-driver. California life sciences companies employ more than 350,000 people directly and one million indirectly with an average salary of $124,000 a year. In 2019 alone, the life sciences industry generated $191.6 billion in revenue, paid over $40 billion in wages, and more than $17.5 billion in federal, state and local taxes.

Every day, at our facility in La Jolla, Pfizer scientists are focused on research and developmen­t of new and innovative cancer therapies, including small molecules, vaccines and immunother­apies. We have championed many of today’s innovative approaches to discover new medicines and fight serious diseases, such as various forms of cancer, including intestinal, kidney, pancreatic, lung and breast cancer.

I work side by side with a group of first-class scientists and a diverse spectrum of specialist­s at Pfizer’s La Jolla site. I have witnessed firsthand the growth in our facilities.

The increase in our investment speaks to the commitment to forwardloo­king when developing treatments, medicines and cures for current and future health challenges.

I am concerned that the vital research and developmen­t done by Pfizer and other California life sciences companies could become stagnant. Without the proper incentives, innovation-based companies are likely to take fewer risks in their quest for new cures, negatively impacting patients, especially those with unmet needs.

The economic impact of the COVID-19 pandemic and anticipate­d budget shortfalls led California to make significan­t budget cuts in 2020, including the eliminatio­n of tax incentives that fueled local life sciences research, developmen­t and investment in the state’s innovation ecosystem. Despite the expected outcome, California now anticipate­s a $75 billion budget surplus.

A recent Milken Institute report found that while California is the nation’s leader in life sciences, other states are rapidly gaining an advantage by offering more robust tax incentives, graduating more life sciences students, and having a lower cost of living. California’s continued leadership in innovation is not guaranteed.

To continue to drive California’s economic recovery, fuel job growth and incentiviz­e investment­s in the research and developmen­t of treatments and cures, including for COVID-19 and future pandemics, California’s elected officials should reinstate the R&D tax credit by including it in the 2022 budget that begins in July.

Investing in California scientists and researcher­s today will lead to new treatments and cures for all tomorrow.

Investing in California scientists and researcher­s today will lead to new treatments and cures for all tomorrow.

Matchett

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