San Diego Union-Tribune

Who was the man with the uneven gait?

University of Pennsylvan­ia archives bring stories of mystery patients’ photos to life

- BY TOM AVRIL Avril writes for The Philadelph­ia Inquirer. This article was provided by Tribune News Service.

He swayed slightly from side to side, his bare feet slapping the ground with each step. Identified only as Rogers, the lanky young man was one of nine neurologic­al patients in a series of sepiatoned “electro-photograph­s,” captured with novel stop-motion technology in Philadelph­ia in the summer of 1885.

The photograph­er was Eadweard Muybridge, better known for using his technique to record the movements of galloping horses. His famous images settled a vigorous debate of the Victorian era: whether the animals, at any point in their stride, lift all four hooves off the ground. (They do.)

Yet Rogers and the other medical patients in the photos have long been a mystery. Historians knew the images had allowed physicians to make precise measuremen­ts of irregular movements caused by disorders of the brain and spinal cord. But what caused the patients’ symptoms? How were they treated? Who were they?

Geoffrey Noble, a neurologis­t who spent months combing through yellowing archives at the University of Pennsylvan­ia, has now cracked the case. Working from limited details in an index that accompanie­d the photos, he matched them with comprehens­ive, handwritte­n medical records for each of the nine patients — revealing their diagnoses, the medicines they took, even where they lived and worked.

The clinical histories provide a rich illustrati­on of an era when physicians were just starting to use technology to unlock the secrets of the human brain, said Noble, who did the research while he was a neurology resident at Penn’s Perelman School of Medicine.

Scientists had begun using microscope­s to study brains from autopsies, discoverin­g the structure of neurons and how they were connected. And Muybridge’s cameras offered a more precise way to characteri­ze neurologic­al disorders in those who were still living — foreshadow­ing the MRIs and other high-tech equipment that would come a century later.

The patients were photograph­ed walking in front of a grid of white strings, hung at the back of a three-sided wooden studio near 36th and Pine streets. The grid appeared in the photos like a big sheet of graph paper, allowing Muybridge’s collaborat­or, Penn physician Francis X. Dercum, to measure the motion of their arms and legs.

Before then, neurologis­ts had only their eyes and ears.

“These doctors had no tests at that time beyond their talking to the patients and examining their patients,” said Noble, now a fellow in neuromuscu­lar medicine at Brigham and Women’s Hospital and Massachuse­tts General Hospital.

Noble did not set out to solve the riddle of the photos. His initial goal was more general: to study the early history of his field. Penn neurology professor Geoffrey Aguirre told Noble about the clinic records, which had been rediscover­ed after a recent renovation, and in November 2020, he started to read.

The 20 volumes came from the outpatient clinic of which Dercum was chief: the Dispensary for Nervous Diseases at the Hospital of the University of Pennsylvan­ia. The entries span a period of 12 years, starting in 1878, just three years after the hospital was founded.

As Noble began to pore over the fading pages, Penn archivist J.M. Duffin told him the university had copies of Muybridge’s photos from the same era. Perhaps some of the subjects were described in the notebooks?

Sure enough, Noble was able to find records for all nine, which he described in September’s issue of the journal Neurology.

“You feel like the patient is coming out of the page at you, 150 years later,” he said.

Rogers, he learned, was H.V. Rogers: an Iowa-born clerk who came to the clinic on 20 occasions over the course of six years. He gave his address as 18 N. Fifth St., in what is now part of the lawn at Independen­ce Mall.

At his first visit, in October

1883, at age 32, Rogers reported suffering from headaches, indigestio­n and constipati­on. Physicians diagnosed him with “general nervousnes­s,” attributin­g it to overwork.

On another visit in 1885, he complained of a constricte­d abdomen and pain in his calves, and was found to have an “ataxic” (unbalanced) gait, which Dercum attributed to a lingering syphilis infection from a decade earlier. At that appointmen­t, Rogers agreed to walk in front of Muybridge’s battery of 12 cameras, each one triggered by an electrical mechanism of the photograph­er’s design.

From the side, the images show him lifting his feet higher than normal and landing with a slight “slap,” Noble said. A second set of images, shot from behind, reveals that Rogers swayed with each step and had a wide stance.

Noble said it was impossible to confirm the diagnosis of syphilis, but he agreed that the patient’s movements were consistent with such an infection — which, in an era with no antibiotic­s, could spread to the spinal cord and brain.

Among the other patients that Noble matched to the photos were a 24year-old laborer who had fallen into a pit, landing on

his head; a 41-year-old homemaker who walked stiffly and experience­d jerking movements of the head and torso, attributed to inflammati­on of the spinal cord; and a 26-yearold “domestic” with a spastic gait, cramps and numbness, blamed on “hysteria.”

Women often were saddled with that vague, unhelpful diagnosis in the Victorian era, and it’s hard to say the true source of the young woman’s complaints. But for one of the other patients, a 64-year-old schoolteac­her then diagnosed with Parkinsoni­sm, Noble thinks he can set the record straight. From looking at the man’s signature and his family history in the notebooks, Noble says that, instead, it is more likely he had a condition called essential tremor.

Many of the treatments prescribed for the patients are now known to be ineffectiv­e. In the case of Rogers, physicians administer­ed two that are toxic: strychnine and mercury.

“We see over time that he’s getting worse,” Noble said. “They’re trying to treat him, and it’s not working.”

Over the years, Rogers also began to experience problems with his eyes. The Penn physicians found that his right optic nerve had atrophied, the retina was

irritated, and the right pupil did not contract as much as the left.

After that, the trail goes cold. But a man with the same name, age, and Iowa birthplace can be found in U.S. Census records, living

until age 71. That was a fairly advanced age for the time, especially for someone with syphilis, but it is likely the same H.V. Rogers, he said.

“The age of death is a little surprising,” Noble said. “But these indolent, chronic infections can burn out over

time. I think this is entirely within the realm of possibilit­y.”

Muybridge, the photograph­er, remained best known for his images of horses. He enlisted an artist to copy them onto a glass disk, which he then projected onto a screen with a device he called the zoopraxisc­ope. When viewed in rapid succession, the images showed the horse in motion — an early forerunner of a movie.

The medical patients, on the other hand, were mostly an enigma, though historians tried over the years to glean clues from studies that Dercum published at the time.

The patient notebooks were rediscover­ed at the hospital in 2017 and transferre­d to university archives, where Duffin’s colleague, J.J. Ahern, ensured their safe storage for posterity. The archivists, aware that medical records from the era were a rare find, were intrigued.

“I knew they were a goldmine,” Duffin said.

What they needed was Noble, someone with medical training and a keen appreciati­on for the past, to extract the nuggets of history from within.

“You feel like the patient is coming out of the page at you, 150 years later.” Geoffrey Noble neurologis­t

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 ?? STEVEN M. FALK TNS ?? J.J. Ahern, a senior archivist at the University of Pennsylvan­ia, displays stop-motion images of a neurologic­al patient named H.V. Rogers, taken in 1885. The photograph­s became a new diagnostic tool for physicians.
STEVEN M. FALK TNS J.J. Ahern, a senior archivist at the University of Pennsylvan­ia, displays stop-motion images of a neurologic­al patient named H.V. Rogers, taken in 1885. The photograph­s became a new diagnostic tool for physicians.

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