San Diego Union-Tribune

CDC SEES 21 MONKEYPOX CASES IN 11 STATES

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The Centers for Disease Control and Prevention has identified 21 monkeypox cases in 11 states, and the numbers are expected to rise, officials reported Friday.

Genetic analysis has revealed that while most of the cases appear to be closely related to the outbreak in Europe, two patients have versions of the virus that seem to have evolved from a monkeypox case identified in Texas last year.

Of 17 patients for whom the agency has detailed informatio­n, all but one were men who had sex with men; 14 had traveled to other countries in the three weeks before their symptoms began. Three patients were immunocomp­romised.

CDC researcher­s have not been able to identify how one patient in an unnamed state acquired the virus. That suggests there is ongoing community transmissi­on at least in that state and possibly others, Dr. Jennifer McQuiston of the CDC told reporters.

“We want to really increase our surveillan­ce efforts,” she said.

Health officials have identified a total of about 400 contacts of 13 patients who also risk becoming infected with monkeypox. Identifyin­g contacts at risk will help officials determine what resources are needed to contain the outbreak.

So far, health officials have delivered about 1,200 vaccine doses and 100 treatment courses to eight states, according to Dr. Raj Panjabi, the White House’s senior director for global health security and biodefense.

Monkeypox’s toll worldwide rose sharply this week, to nearly 800 cases as of Friday. The spread of the virus to at least 31 countries outside Africa, where it is endemic, has raised alarm among scientists and public health officials.

Health officials in some countries are asking anyone who tests positive for monkeypox to isolate at home. Britain, which has recorded the most cases, has urged patients to abstain from sex until their symptoms have cleared, to use condoms for eight weeks after that and to limit interactio­ns with pets and other animals, which may become infected.

As the outbreak expands, health officials worldwide are rushing to gather vaccines and treatments. The options are severely limited.

The United States is among the few countries to have stockpiled vaccines and drugs for smallpox as a precaution against its return. Monkeypox is closely related to smallpox, and the vaccines and drugs are expected to be about as effective.

In theory, at least two drugs and two types of vaccines are available to combat a monkeypox outbreak, but most of these have been tested primarily in animals.

In a recent study of the two drugs in seven patients, only one appeared to offer any benefit, while the other produced toxic side effects.

The older of the two vaccine options was used to eradicate smallpox and can cause harsh side effects, including heart problems and death. Most doses have been in storage for decades and may have lost their effectiven­ess.

The second vaccine option, made by Danish company Bavarian Nordic, was approved by the Food and Drug Administra­tion in 2019 to prevent smallpox and monkeypox. Called Jynneos in the United States, it is safer than earlier vaccines, but supplies are even more limited.

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