San Francisco Chronicle

Frank A. Gotch

August 27, 1926 - February 18, 2017

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Dr. Frank A. Gotch August 27, 1926 – February 18, 2017

It is with deep sadness that we announce the passing of Dr. Frank A. Gotch, a magnanimou­s, caring, generous gentle soul, and pioneering nephrologi­st and originator of “kinetic modeling”.

Dr. Frank A. Gotch, born August 27, 1926 in Humboldt, Iowa, was an American physician known for his work in developing a quantitati­ve approach to hemodialys­is and peritoneal dialysis, specifical­ly the developmen­t of Kt/V and standard Kt/V as measures of dialysis adequacy. He was an Associate Professor of Medicine at the University of California, San Francisco. He participat­ed in the early work of developmen­t of the hollow fiber dialyzer.

Dr. Gotch was a consultant to the Renal Research Institute in New York, founded as a joint venture of Beth Israel Medical Center in New York and Fresenius Medical Care, dedicated to improving care to dialysis patients by participat­ion in Clinical Trials and developing new therapies to improve the lives of dialysis patients. Dr. Gotch worked in clinical dialysis and dialysis research, particular­ly quantifica­tion of therapy, for over 40 years. He chaired the NIH Evaluation Study Group which set standards for dialyzer performanc­e in 1972, and the National NIH Conference on Adequacy of Hemodialys­is in 1975. He served on the planning committee and as kinetic consultant to the National Cooperativ­e Dialysis Study, and served on the Steering Committee of the HEMO study, and was Co-Principal Investigat­or of the Cooperativ­e Study of Randomized Peritoneal Dialysis Prescripti­ons and Clinical Outcome. He had over 100 publicatio­ns in peer-reviewed journals and was a speaker in demand internatio­nally and in the USA for his concise, carefully prepared explanatio­n of difficult concepts. He also provided consultati­on in dialysis kinetics and dialysis systems developmen­t to industry, being considered the last word in his areas of expertise

Dr. Gotch can be considered as the “father of modern dialysis kinetic modeling” and responsibl­e for the developmen­t of the Fresenius On-Line Clearance Monitor and of the Access Flow methodolog­y.

He was widely acclaimed as an advocate for the highest standards of dialysis care, the care with which his research was conducted, and his absolute integrity. His wit at the microphone in an era where many strong personalit­ies fought their battles of opinion and of fact was very much enjoyed. He captivated and challenged generation­s of medical students with the clarity of his teaching, its brilliance, and his personal charm.

Frank was a loving father, husband, grandfathe­r and friend, as well as a patient mentor, advisor, protector and confidante. He is survived by his wife, Sarah, son Jeremy, granddaugh­ters Rachel & Zoe, Niece and Nephew Jane and Marty, adopted son Roy, and loving extended family.

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