Broncos’ Osweiler delivers

Denver quarterback Brock Osweiler ran for one touchdown and threw for two more on an injury-filled Thursday night to lead the Broncos past host Indianapolis 25-13.

Osweiler was 12-for-17 with 194 yards and took the Broncos (5-9) on three second-half scoring drives. Cal alum C.J. Anderson ran 30 times for a season high 158 yards.

Osweiler entered the game when Trevor Siemian went to the locker room with a sprained left shoulder after Barkevious Mingo drove him into the ground on the Broncos’ second series. Siemian did not return and it’s unclear whether he’ll be able to play at Washington on Dec. 24.

The scariest moment came with 14:01 left in the second quarter, when Denver linebacker Deiontrez Mount appeared to make helmet-to-helmet contact with Indy tight end Brandon Williams on a punt. Williams was knocked over backward and stayed on the ground before trainers strapped him to a backboard and removed his face mask. Head coach Chuck Pagano said after the game that Williams had a concussion and was back in the team’s training room after being taken to a hospital.

The Colts (3-11) wasted an early 10-0 lead and have lost five in a row, the longest skid of Pagano’s six-year tenure. Briefly: ESPN reported that the Cardinals are putting running back Adrian Peterson on season-ending IR because of a neck injury suffered Nov. 26 against the Jaguars . ... Jacksonville running back Leonard Fournette expects to play Sunday against the Texans despite missing two days of practice after injuring his right quad Sunday against the Seahawks. ... The Giants placed top offensive lineman Justin Pugh on injured reserve with a back injury.