San Francisco Chronicle

Neuralink wants chips in the brain

Neuralink says it has created a device, seen in an artist’s rendering, that could one day wire data links directly to the brain. The company is backed by Elon Musk.

- By John Markoff

Elon Musk aspires to make inserting a computer connection into your brain as safe and painless as Lasik eye surgery.

On Tuesday, Musk appeared at the California Academy of Sciences to announce that Neuralink, a company in which he has invested $100 million, had developed a “sewingmach­inelike” robot that can implant ultrathin threads deep into the brain.

The company claims the system will eventually be capable of reading and writing vast amounts of informatio­n. But as with many of Musk’s other ventures, like spaceships or futuristic tunnels, one of the biggest challenges may be for his scientists to match his grand vision.

Musk, the billionair­e chief executive officer of electricca­r maker Tesla, who has famously claimed that he “wants to die on Mars, just not on impact,” has a reputation for doing bold things, as well as making even bolder claims that stretch credulity.

Like artificial intelligen­ce, the idea of

inserting a device into the brain that would allow speedy communicat­ion between humans and computers veers quickly into science fantasy.

In his 1984 science fiction novel “Neuromance­r,” William Gibson posited the idea of something he called a “microsoft,” a small cartridge directly connected to the brain through a socket to provide a human user with instant knowledge, such as a new language.

In a briefing Monday, Neuralink executives acknowledg­ed they had a “long way to go” before they could begin to offer a commercial service. But they were ready to discuss their work publicly. Musk was not at the meeting.

“We want this burden of stealth mode off of us so that we can keep building and do things like normal people, such as publish papers,” said Max Hodak, Neuralink’s president and one of the company’s founders.

Musk has been active in trying to help solve the engineerin­g challenges that Neuralink faces, according to Shivon Zilis, project director at Neuralink. The company has received $158 million in funding and has 90 employees.

While the most fantastica­l visions for a braincompu­ter may be a long way off, Musk may have found a potential medical use.

Hodak shared Musk’s optimism that Neuralink technology might one day — relatively soon — help humans with an array of ailments, like helping amputees regain mobility or helping people hear, speak and see.

The company is hoping to begin working with human subjects as soon as next year.

Neuralink says surgeons would have to drill holes through the skull to implant the threads. But in the future, they hope to use a laser beam to pierce the skull with a series of tiny holes.

They plan to work with neurosurge­ons at Stanford University and possibly other institutio­ns to conduct early experiment­s. Jaimie Henderson, a professor of neurosurge­ry at Stanford and a specialist in the treatment of epilepsy and the use of a treatment known as Deep Brain Stimulatio­n, is an adviser to Neuralink, according to Hodak.

In a demonstrat­ion at a Neuralink research lab Monday, the company showed a system connected to a laboratory rat reading informatio­n from 1,500 electrodes — 15 times better than current systems embedded in humans. That’s enough for scientific research or medical applicatio­ns.

Independen­t scientists cautioned that successes in laboratory animals might not translate into humans and that human trials would be required to determine the technology’s promise.

In a seemingly unplanned moment at the Cal Academy, Musk also acknowledg­ed that Neuralink’s research had progressed beyond rodents to nonhuman primates, Wired magazine reported. It said that it’s only because of a records request filed by the Gizmodo website that Neuralink’s affiliatio­n with the primate research center at UC Davis is public knowledge. That affiliatio­n has apparently progressed: “A monkey has been able to control a computer with its brain, just FYI,” Musk said during a questionan­danswer session after the presentati­on.

Recently, the most advanced data for animal studies has come from the Belgian company Imec and its Neuropixel­s technology, which has a device capable of gathering data from thousands of separate brains cells at once.

One of Neuralink’s distinguis­hing techniques is that it places flexible threads of electrodes in proximity to neurons, the tiny cells that are the basic building blocks of the brain.

The ability to capture informatio­n from a large number of cells and then send it wirelessly to a computer for later analysis is believed to be an important step to improving basic understand­ing of the brain.

The threads are placed using thin needles, and a socalled computervi­sion system helps avoid blood vessels on the surface of the brain. The technique involves inserting a bundle of threads that are each about a quarter of the diameter of a human hair.

The flexible threads are actually thin sandwiches of a cellophane­like material that insulates conductive wires that link a series of minute electrodes, or sensors, much like a strand of pearls.

They can be inserted in different locations and to different depths, depending on the experiment or applicatio­n. Medical research and therapy may focus on different parts of the brain, such as centers for speech, vision, hearing or motion.

The flexibilit­y of the Neuralink threads would be an advance, said Terry Sejnowski, the Francis Crick Professor at the Salk Institute for Biological Studies near San Diego.

However, he noted that the Neuralink researcher­s still need to prove that the insulation of their threads could survive for long periods in a brain’s environmen­t, which has a salt solution that deteriorat­es many plastics.

Despite the gala introducti­on Tuesday at the Cal Academy in Golden Gate Park, Neuralink is certain to have plenty of competitio­n.

Over the past decade, the Pentagon has financed research both for basic brain sciences and to develop robotic control systems that would permit brain control of prosthetic devices.

Researcher­s with funding from the Defense Advanced Research Projects Agency have been able to create interfaces allowing quadripleg­ics to independen­tly manipulate robot arms to perform manual tasks like drinking.

Independen­t scientists cautioned that successes in laboratory animals might not translate into humans and that human trials would be required to determine the technology’s promise.

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 ?? Frederic J. Brown / AFP / Getty Images ?? Tesla CEO Elon Musk, here unveiling a new car model in March, said Neuralink is making progress on linking brains with computers and hopes to begin testing on people next year.
Frederic J. Brown / AFP / Getty Images Tesla CEO Elon Musk, here unveiling a new car model in March, said Neuralink is making progress on linking brains with computers and hopes to begin testing on people next year.

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