San Francisco Chronicle

N.Y. TIMES CROSSWORD

Biotechnol­ogy

- By Victor Barocas

ACROSS 1 Homeowner’s action, for short 5 Things blockers block 8 1979 film inspired by Janis Joplin’s life 15 Indistinct shape 19 Receptioni­st on “The Office” 20 Be bothered by 22 Island nation west of Fiji 23 Possible consequenc­e of default, in brief 24 Wildflower with spiky, purplish blooms 25 Secure 26 Ruling family of Edward I 27 Finished 28 Adam’s ____ (water) 29 Hole in one’s head 31 Humpty Dumpty, e.g. 32 “Dallas” family name 33 The Anne of “Anne of the Thousand Days” 35 Feverish 36 Put back on 38 Insinuatin­g 39 - 40 James who won an Emmy two years in a row for the same role on different shows 42 - 45 Ignorant person, in slang 47 Security-system array 49 Total 51 Angered by 53 Ancient monuments 54 Gaston ____, “The Phantom of the Opera” novelist 55 Latte choice, informally 58 The “she” in the lyric “She would merengue and do the cha-cha” 59 W.W. I French biplane 60 Capital of Albania 61 Like much of Iowa 63 1980 Olympic hockey champs 66 Up 68 Shark fighters 70 “Believe ____ not!” 71 Biological manipulati­on suggested four times by this puzzle 74 First AfricanAme­rican Davis Cup player 75 Beethoven’s birthplace 76 Comprehens­ion 77 Tender spot? 78 Like the sun god Inti 79 Some liturgical vestments 81 ____ de Triomphe 83 It’s down in the dumps 86 First National Leaguer to hit 500 home runs 87 Fall color providers 88 Some instant coffees 90 Cheyenne Mountain org. 92 Stays out of 93 Closes in a thin membrane 95 Disappoint­ing response to an applicatio­n 98 Remarkable ability of a starfish 99 Use a rototiller on, say 101 Lack of variation 103 “ER” actress Laura 105 Turn out 106 Service with more than 1.5 billion users 107 Home of the Latino Walk of Fame, informally 108 Composer of the “London” symphonies 111 Big e-cigarette brand 113 Anti-athlete’s foot brand 115 Good for leaving handprints in 116 State without reservatio­ns 117 - 119 Provider of child support? 120 - 121 Polynesian carving 122 Dreamer 123 Half in advance? 124 Unique individual 125 Starting point 126 Broadway’s “____ Todd” 127 “Hamilton” Tony nominee Phillipa ____ 128 Loch ____, site of Urquhart Castle DOWN 1 Goes through physical therapy 2 Anon 3 Beethoven’s only opera 4 As a rule 5 City that ancient Greeks called Philadelph­ia 6 Christian with a big house 7 Winter vehicle 8 Mike and Carol Brady, e.g. 9 Berry receiving much attention in the 2000s 10 Bambi’s aunt 11 Bit of ancient script 12 Ingredient in some health-food supplement­s 13 Not occurring naturally 14 Romanian-born writer once in the French Academy 15 Cook on the outside 16 Tribe of Moses and Aaron 17 Available to the public 18 Wimbledon champ, 1976-80 21 First takes 29 Gag item floating in Halloween punch 30 Brother on “Frasier” 32 Breadwinne­r 34 Ancient Dead Sea land 37 Woozy 39 - 40 Rooms with views 41 Forecast 42 - 43 Phrase of agreement 44 Subject for Kinsey 46 Olden Tokyo 48 Flower part 50 Roman emperor before Hadrian 52 “Nyah, nyah!” e.g. 55 Nursery sight 56 Insurance for the crash-prone 57 Big story 60 Start of a countdown 62 Composer Schoenberg 64 Repair material 65 Skepticall­y 67 Apostle called “the Zealot” 69 Launched 71 Didn’t know but said something anyway 72 Midlength records, for short 73 Full of spirit 78 From Shiraz or Tabriz 80 Country star Womack 82 Greenbacks 84 1990s-2000s compact car 85 Smelter’s supply 87 Locale for un capitaine 88 It doesn’t need land to land 89 Sometimes-white animal 91 Rackets 94 Smiles smugly 96 Twist together 97 X’s 100 Chafe 102 QB protection squads 104 Companions of Dionysus 105 John Wilkes Booth’s actor brother 106 Wikipedia’s logo 107 Refrain from nursery singing 108 “In time we ____ that which we often fear”: Shak. 109 Devoted 110 Make into a couple 112 Magazine with the motto “Cure ignorance” 114 Staff note 117 - 118 First name in spy literature 120 -

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