Santa Fe New Mexican

Funding is the lifeblood of medical research

- Wyatt Decker, M.D., is vice president at the Mayo Clinic and chief executive officer of the Mayo Clinic in Arizona.

To ask the question today, “Will there ever be a cure for cancer?” you may get the answer: “No, there will be cures for cancer.” What seemed so distant not long ago is fast becoming reality for different types of cancer. We have seen amazing advancemen­ts and momentum that is both encouragin­g to the medical community and provides hope for millions of patients. But that momentum is at risk.

In Washington, D.C., there has been talk of cuts to research funding through the National Institutes of Health. This funding is the lifeblood of medical research and a catalyst for philanthro­py and other research backing nationwide.

We are relieved to see that, under a recent bipartisan spending deal in Congress, NIH will get a short-term funding boost. However, there is still concern about the longer term for 2018 and beyond, when the administra­tion is considerin­g deep cuts. We know the challenges of balancing innovation with costs. Make no mistake: Research isn’t an expense, but an investment in our nation’s economy and health of our fellow citizens.

Funding research means funding hope

Understand­ing the biological processes that contribute to human disease and proposing new treatments, as well as clinical trials and validation, all take time and are necessary — and sometimes expensive — steps along the path to cures.

That’s why we at Mayo Clinic, as a not-for-profit organizati­on, heavily invest in medical research. NIH funding has remained flat over the past decade while Mayo Clinic has doubled its investment in research. Knowing that cancer rates continue to rise, our physicians and scientists are focused on fighting cancer, exploring the emerging fields of immunother­apy, regenerati­ve medicine, individual­ized medicine, data aggregatio­n and artificial intelligen­ce. We do all we can to advance innovation.

We have many examples of this right here in this region of the country: Multiple myeloma. Thanks to a dedicated research team at Mayo Clinic and beyond over the past 10 years, survival rates for this disease of plasma cells have doubled. At Mayo Clinic in Arizona, we have a team dedicated to continuing this trend by studying innovative treatments to prompt the body’s immune system to combat the disease and another that infuses a virus in cancer cells to kill them.

Breast cancer blood screening. Mayo Clinic is participat­ing in a large-scale clinical trial aimed at developing a simple blood test to screen for early stages of breast cancer, when there is a greater chance for cure.

Teaming with industry. A recent example is Cologuard, a noninvasiv­e, stool-based DNA screening test for colorectal cancer, the second leading cause of cancer death in the U.S. Our team and an industry collaborat­or were able to rapidly translate a lab discovery to a simple test that is more accurate than previous screenings. In many situations, this test is a suitable alternativ­e colonoscop­y.

We know medical research will offer solutions and a brighter future, but we need to sustain funding to get there.

Patient-centered thinking

Even with our significan­t efforts, generous benefactor support and collaborat­ions with industry, we, like many other academic medical centers, rely on NIH funding for sustainabi­lity. NIH funding is a key economic driver in the health care industry. Who knew that today we’d be looking for scant particles of DNA in blood samples to detect cancer, or developing individual therapies for patients based on their genomes?

We know medical research will offer solutions and a brighter future, but we need to sustain funding to get there. Cuts in funding would mean setbacks on discovery and cures, and diminished hope for patients and families. Mayo Clinic believes in putting the patient at the center of this discussion. Our hope is that health care in the U.S. includes strong, long-term and sustainabl­e federal support for research.

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