Blue Jays beat Red Sox on somber night.

TORONTO — Curtis Granderson hit a walk-off homer in the 10th inning to give the Toronto Blue Jays a 4-3 win over Boston on Tuesday night and hand the Red Sox their seasonworst third straight defeat.

Boston (17-5) still owns the best record in the majors.

Granderon’s his third home run of the season came off Red Sox closer Craig Kimbrel (0-1), a towering solo blast off the facing of the third deck in right field. He went 3 for 5 with three RBIs in the Blue Jays’ first game since a deadly van attack in Toronto a day earlier. The victims of the attack, which killed 10 and injured 14, were honored along with first responders before the game.

Tyler Clippard (3-0) worked a scoreless 10th for the win.

REDS 9, BRAVES 7 (12 INNINGS)

In Cincinnati, Tyler Mahle lost his no-hit bid on Freddie Freeman’s homer in the seventh inning, and the Reds blew a big late lead before Scooter Gennett connected in the 12th.

Gennett hit his second homer of the game off left-hander Max Fried (0-1) for his first career game-ending shot.

Freeman started the Braves’ late seven-run surge with his homer off Mahle, only the third ball the Braves managed to get out of the infield against the rookie right-hander.

YANKEES 8, TWINS 3

In New York, Didi Gregorius had another big game at Yankee Stadium with a two-run homer and three RBIs, and Gary Sanchez homered twice to help CC Sabathia and New York romp past the Minnesota.

Aaron Judge hit his seventh home run as the Yankees went deep four times for the second straight night. Gleyber Torres had a pair of hits and his first RBI for New York, which extended a winning streak to four for the first time under new manager Aaron Boone and sent the Twins to their season-worst fifth consecutive loss.

Sabathia (1-0) rarely allowed hard contact in his second start back from the disabled list and gave up an unearned run and two hits in six innings. He is 20-9 in 39 regular-season starts against the Twins.

CUBS 10, INDIANS 3

In Cleveland, Kyle Schwarber hit two solo home runs and Chicago defeated the Indians in the first meeting between the teams since their classic 2016 World Series.

The Cubs won three games in Cleveland’s ballpark during the 2016 Series and continued the trend against Josh Tomlin (0-3), who allowed all four homers. Schwarber connected leading off the second and fourth. Willson Contreras went deep in the third and Ian Happ homered in the fourth.

MARINERS 1, WHITE SOX 0

In Chicago, Marco Gonzales and four relievers combined on a five-hitter, Mitch Haniger singled home the only run and Seattle beat the White Sox.

At 5-15, the rebuilding White Sox are off to their worst start since the 1950 season.

DIAMONDBACKS 8, PHILLIES 4

In Philadelphia, Alex Avila homered among his three hits and drove in two runs, Robbie Ray struck out 11 while pitching into the fifth inning Arizona beat the Phillies.

Daniel Descalso and Jarrod Dyson also homered for the Diamondbacks, who upped their NL-best record to 16-6.

BREWERS 5, ROYALS 2

In Kansas City, Mo., Lorenzo Cain homered while reaching base four times in his return to Kauffman Stadium, and Milwaukee beat Kansas City.

Travis Shaw added a three-run homer for the Brewers, while Zach Davies (2-2) pitched six innings of four-hit ball. Ryan Braun had two hits, walked twice and drove in a run.

ATHLETICS 3, RANGERS 2

In Arlington, Texas, Jed Lowrie hit a tiebreaking double in the seventh inning, and Oakland tagged Texas’ Cole Hamels with his fourth loss before the end of April for the first time in the left-hander’s career.

Texas slugger Adrian Beltre exited with a left hamstring strain in the eighth after pulling up at first base on what would have been a double but was instead a single for his 3,075th career hit.

METS 6, CARDINALS 5 (10 INNINGS)

In St. Louis, Jay Bruce hit a tiebreaking homer in the 10th inning, Yoenis Cespedes launched a majestic, three-run shot and New York rallied to beat the Cardinals.

Bruce began the game batting .194 but broke out of his slump with three hits, including an RBI triple.

ANGELS 8, ASTROS 7

In Houston, Mike Trout hit his major leagueleading 10th homer and Los Angeles overcame another shaky start by Shohei Ohtani to beat the Astros, tying a team record with their 11th straight road win.

Andrelton Simmons homered twice with a career-high five RBIs, connecting for a tiebreaking, three-run drive in the seventh inning. The Angels also won 11 in a row outside Anaheim in 1988.

ROCKIES 8, PADRES 0

In Denver, Trevor Story hit the second grand slam of his career, Kyle Freeland scattered three hits over seven sharp innings and the Rockies beat San Diego.

Colorado outfielder Noel Cuevas notched his first major league hit— a single down the line that looked like a sure double before he slipped on the first base bag.