NFL MATCHUPS

The NFL’s record in containing the coronavirus took a major hit when multiple members of the Tennessee Titans tested positive following last week’s win over Minnesota. Now, a matchup between Tennessee and Pittsburgh — both of which are 3-0 — has been delayed.

On Saturday, the NFL suspended the Patriots-Chiefs game after New England quarterback Cam Newton tested positive for the coronavirus.

Last week’s record: 10-6

Overall record: 27-21

BROADCAST LOCALLY

Chargers at Buccaneers

11 a.m. CBS

Line: Buccaneers -7 | Total: 43.5

It’s good to be the Buccaneers (2-1). Tom Brady is settling in well and the team’s defense has proved that it is a force. An injury to wide receiver Chris Godwin takes away a little of their offensive upside, but Tampa Bay seems like it might be a playoff team — one that could struggle against the elites, but also one that can handle middling teams just fine.

The Chargers (1-2) likely also view themselves as a playoff team, but while there will be plenty of focus on whether Tyrod Taylor or Justin Herbert will start at quarterback, the larger concern is on defense, where Los Angeles expects to be without defensive end Melvin Ingram, defensive tackle Justin Jones and cornerback Chris Harris Jr. That could lead to more time for Brady to throw, and more room for wide receiver Mike Evans to get open. The potential is there for a Tampa Bay blowout, but a narrower win should be expected.

Pick: Chargers +7

Browns at Cowboys

11 a.m. Fox

Line: Cowboys -4.5 | Total: 55.5 The Cowboys (1-2) have played three exciting games already this season, but they’ve lost two of them, which isn’t a strong endorsement of the coach Mike McCarthy era. The yardage has come in huge chunks on both sides of the ball: Dak Prescott’s 1,188 passing yards are the fifth-most a player has ever had through three weeks and the Cowboys’ opponents are averaging 404.7 yards per game (while scoring an average of 32.3 points per game).

The Browns (2-1) have a shot to get to 3-1 for the first time since 2001 with a huge day from either quarterback Baker Mayfield or running Nick Chubb — or both. Dallas should be favored, but this could come down to which team has the ball last.

Pick: Browns +4.5

Bills at Raiders

2:25 p.m. CBS

Line: Bills -3 | Total: 52

What in the world is going on with the Bills’ (3-0) defense? The team returned nearly everyone from last season’s stout crew and they’ve looked terrible. They’ve allowed 25.7 points and 380 yards per game, and those numbers don’t appear to be fluky.

The bad defense has ... worked out fine thus far. Their success owes to the emergence of quarterback Josh Allen, who has thrown for at least 300 yards in each game and has an absurd passer rating of 124.8, now that he’s got a true No. 1 target in receiver Stefon Diggs. But if Buffalo is going to keep this strong start going and win a road game against the fairly decent Raiders (2-1), the defense will have to figure things out. Don’t bet against it.

Pick: Bills -3

Eagles at 49ers

6:20 p.m NBC

Line: 49ers -7 | Total: 45

The 49ers (2-1) are still nowhere near full strength. Cornerback Richard Sherman is at least a week away from returning, as is wide receiver Deebo Samuel. And the team will have to watch for newly injured running back Jerick McKinnon (ribs) and cornerback Emmanuel Moseley (concussion).

The Eagles (0-2-1), in fairness, have been playing so poorly that they’d likely lose to San Francisco even if Nick Mullens and the Expendables had to take the field for a second consecutive week.

Pick: 49ers -7

Falcons at Packers

6:15 p.m. Monday ESPN

Line: Packers -7.5 | Total: 57.5 Aaron Rodgers has a reputation as a quarterback who rises to the biggest moments.

Rodgers looks very comfortable in coach Matt LaFleur’s offense, and the Packers have more points through three games (122) than any other team in Green

Bay history. Put that offense up against the Falcons (0-3), who have looked terrible on defense and have blown enormous leads in back-to-back weeks, and you might expect a blowout.

But Green Bay’s offense is going to slow down on occasion, and a game at home against a lowly opponent might be a moment for the whole team to relax a little. A win should still be expected, but maybe not one by more than a touchdown.

Pick: Falcons +7.5

OTHER GAMES

Colts at Bears

11 a.m.

Line: Colts -2.5 | Total: 45

The Colts (2-1) have followed their embarrassing Week 1 loss to Jacksonville with a pair of convincing victories over fairly weak competition. That qualifies as a good start, and it is one that is much more sustainable than the perfect record of the Bears (3-0). Rarely has a team seemed so unjustifiably undefeated, but Chicago has been bizarrely magical in the fourth quarter. Last week’s come-from-behind win over Atlanta convinced the Bears that Nick Foles should be starting at quarterback, but they probably can’t rely on the Colts to collapse like Detroit and Atlanta did.

Pick: Colts -2.5

Ravens at Washington

11 a.m.

Line: Ravens -13 | Total: 47 Everyone loves a pile-on, and Twitter was ablaze Monday with mentions that Lamar Jackson and the Ravens (2-1) have never won a game in which they were trailing at halftime. It’s a valid statistic that ignores the fact that Jackson has lost only four regular-season games over the past three seasons. As three of those four losses came against Patrick Mahomes, and Mahomes is very unlikely to suit up for the Footballers (1-2), a Baltimore win that gets the team back on track seems fairly predictable. Will they justify the two-touchdown spread? You shouldn’t put it past them.

Pick: Ravens -13

Vikings atTexans

11 a.m. Fox

Line: Off | Total: Off

Tthe Vikings (0-3), who played the Titans last week, appear on track to play. This was already seeming like a potential blowout, with Deshaun Watson and the Texans (0-3) getting a chance to work out their frustrations on one of the worst defenses in the NFL. If the game is played, and Minnesota has to take the field with almost no in-person preparation, it could get ugly.

Pick: Texans

Cardinals at Panthers

11 a.m.

Line: Cardinals -3.5 | Total: 52 Despite a surprising loss to Detroit last week, the Cardinals (2-1) have established that their offense must be reckoned with. Quarterback Kyler Murray is a budding star and the offseason trade for wide receiver DeAndre Hopkins looks better every day, as Hopkins is leading the NFL with 32 catches for 356 yards and the cost Arizona paid for him (running back David Johnson and two draft picks) is negligible since Kenyan Drake has done quite well in Johnson’s place. The Panthers (1-2) are significantly hampered by the absence of running back Christian McCaffrey, and while Carolina won on the road last week, that was the result of turnovers that the Cardinals are unlikely to give them.

Pick: Cardinals -3.5

Seahawks at Dolphins

11 a.m.

Line: Seahawks -6.5 | Total: 54.5 The Seahawks (3-0) are undefeated despite their defense allowing almost 500 yards a game. That’s part oddity and part testament to Seattle’s offense, with Russell Wilson outplaying even Patrick Mahomes and Lamar Jackson so far this season. Wilson has an NFL-record 14 touchdown passes through three weeks and would potentially have 15 if not for DK Metcalf having let a sure 62-yard touchdown be knocked away for a fumble and a touchback, which allowed Dallas to finally experience the other end of Leon Lett’s infamous blunder. (Metcalf made up for his mistake by catching the go-ahead score with less than two minutes remaining.)

The Dolphins (1-2), meanwhile, had a nice long break after their huge win over Jacksonville on Thursday of Week 3. Ryan Fitzpatrick is unpredictable and prone to mistakes, but he is also likely excited for a shot at Seattle’s defense. A shootout would still favor the Seahawks, but the score could be fairly close.

Pick: Dolphins +6.5

Saints at Lions

11 a.m.

Line: Saints -4.5 | Total: 54.5

Few would have expected these teams to come into Week 4 with the same record, but it’s also doubtful anyone expected the Saints (1-2) to have allowed 31.3 points a game. A close look shows a team that has acquitted itself well against the run but has struggled against the pass far more than expected while dealing with some fairly explosive competition. With all that in mind, the Lions (1-2) might put up a bit of a fight. Coming off an upset of Arizona, Detroit has run the ball a lot this season thanks to the ageless Adrian Peterson, but the potential is always there for a big passing day from Matthew Stafford. The expected return of wide receiver Michael Thomas could be a corner-turning moment for the New Orleans offense, but on the road they are a questionable favorite.

Pick: Lions +4.5

Jaguars at Bengals

11 a.m.

Line: Bengals -3 | Total: 48.5

At a glance, the passing defense of the Jaguars (1-2) looks bad — they’re ranked 19th in total passing yards allowed — but if you delve in a bit deeper, things are much worse. They are allowing an NFLworst 118.6 passer rating, have had only three sacks over three games and, according to Football Outsiders, are the least efficient unit by a country mile, making even the Jets seem competent by comparison.

Enter Joe Burrow of the Bengals (0-2-1) who hasn’t won a game yet, but has 628 yards passing, five touchdowns and no interceptions over his past two starts. Rookies are unpredictable, and the Jaguars’ offense isn’t quite as bad as it looked last week, but Cincinnati is a rightful favorite.

Pick: Bengals -3

Giants at Rams

2:05 p.m.

Line: Rams -12 | Total: 48.5

The Rams (2-1) are likely smarting from a wild ride last week in which they were getting blown out, 28-3, by Buffalo, then charged back to take the lead in the fourth quarter, only to have Josh Allen rip out their hearts in the final seconds. Crushing the spirit of the Giants (0-3) in retaliation isn’t really possible, as the Giants’ spirit should have been permanently crushed in their humiliating loss to the 49ers’ backups last week. That won’t stop Los Angeles from trying.

There’s no question that the Rams could win this game by 12 or more if they kept their concentration and wanted to make a point, but expecting a slightly narrower margin — with fairly little drama to it — is far more realistic.

Pick: Giants +12