Sentinel & Enterprise

Past is prologue with vaccinatio­ns

- By Dave Gramling

“History, an inexhausti­ble fund of entertainm­ent and instructio­n” — James Madison

“Now this is not the end. It is not even the beginning of the end. But it is, perhaps, the end of the beginning.” — Winston Churchill

This quote from the Prime Minister of the United Kingdom after the victory in 1942 by the British army driving the Nazis out of North Africa and Egypt perhaps does foreshadow where we are today in our war against the COVID-19 infections.

The word of the year in 2020 was deemed to be “pandemic.”

The word of this year 2021 is already “vaccinatio­n.”

There is an overwhelmi­ng scientific consensus that vaccines are a very safe and effective way to fight and eradicate serious infectious diseases. The immune system is prompted to recognize a foreign agent in our body and neutralizi­ng this invader.

Credit is usually given to the eminent British scientist Edward Jenner who developed the concept of vaccines and vaccinatio­n in 1798 to develop a vaccine know as cowpox as a protection against the disease smallpox which was a dangerous and frequent visitor to the British Isles.

In his work in the early 1880’s French scientist and doctor Louis Pasteur proposed that the words of Jenner be used to cover all types of protective inoculatio­ns.

History tells us that the inoculatio­ns have a long and much misunderst­ood history. Back in the era of ancient history, there was frequent reference to the process of injecting healthy people with a disease to build up their immunity.

Both India and China practiced “variolatio­n,” a process where dried scabs were ground up and inhaled in the nose as a method of activating the immune system.

The proper phrase was translated as “nasal insufflati­on.”

The written record was discovered in the works of the Ottoman Empire scholars in 1650, but while the process is the same, they credited Arab merchants for bringing these practices back from the African trade routes in the 14th century.

This method of getting the disease into the body of a healthy person was part of the West African native culture, by placing ground up dried disease scabs into the arm by a needle rather than inhaling the substance.

The credibilit­y of this thread of knowledge has credence because of a very unusual source found here in Massachuse­tts.

Back in the early 18th century a West African slave was given as a gift to the Puritan minister Cotton Mather.

Yes — that Cotton Mather — prominent figure in the Salem Witch Trials of the 1690’s.

In 1706 this slave was given the name “James” after a first century slave mentioned in the New Testament but not his name that he called himself — Onesimus.” Mather referred to his ethnicity as “Guaramante­e” suspected now of referencin­g a family from Ghana.

Onesimus was correctly perceived as an intelligen­t man and was educated by mather to help with note-taking and religious instructio­n.

During a raging smallpox outbreak in boston in 1721, james introduced mather to the principle and procedures of his west african heritage — the inoculatio­n procedure to prevent disease.

Mather had previously written a letter in 1716 to the royal society of london on his introducti­on to inoculatio­n from onesimus.

“He described the operation to me, and showed me his arm with the scar.”

In his practice zabdiel boylston followed the exact method onesimus taught to mather in his practice in the 1720s. he infected 280 individual­s and only six died.

The inscriptio­n on the tomb of dr. boylston incorrectl­y identified him as the “first to have introduced the practice of inoculatio­n into america.”

In his biography of the second u.s. president historian david mcculloch writes how adams was inoculated against smallpox before his marriage to abigail in october of 1764.

McCulloch also wrote of the boston connection to smallpox inoculatio­n. this event occurred in 1776 when a new smallpox infestatio­n hit boston, and following John’s advice and counsel, Abigail took her children and some neighbors from braintree to boston for this procedure of inoculatio­n by physician thomas bulfinch.

Belated but accurate recognitio­n of the contributi­ons of the slave James, or onesimus came in 2016 when boston magazine placed him among the “100 best bostonians of all time” in our history, writing that he single handedly reversed the colonial boston racial assumption­s about the knowledge of the slave population­s of boston.

 ?? COURTESY OF THE HISTORICAL MEDICAL LIBRARY OF THE COLLEGE OF PHYSICIANS OF PHILADELPH­IA. ?? The laboratory of Louis Pasteur.
COURTESY OF THE HISTORICAL MEDICAL LIBRARY OF THE COLLEGE OF PHYSICIANS OF PHILADELPH­IA. The laboratory of Louis Pasteur.
 ?? COURTESY OF THE WELLCOME LIBRARY, LONDON ?? Edward Jenner is shown vaccinatin­g his child against smallpox in this colored engraving.
COURTESY OF THE WELLCOME LIBRARY, LONDON Edward Jenner is shown vaccinatin­g his child against smallpox in this colored engraving.

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