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Can certain foods really stave off dementia?

What science says about diet and cognitive decline

- By Amelia Nierenberg

Walnuts can improve cognitive function. Blueberrie­s can boost memory. Fish oil supplement­s can lower your risk of Alzheimer’s disease.

You may have noticed these buzzy “brain food” claims scattered across online health articles and social media feeds. But can certain foods or diets really stave off or prevent dementia?

Experts say that while nutrition studies are notoriousl­y challengin­g to carry out, there is a compelling and ever-growing body of research that does suggest that some foods and diets may offer real benefits to an aging brain. So we spoke with two dozen researcher­s and pored over the research to better understand the links between diet and dementia.

Pillars of a ‘brain-boosting’ diet

Scientists don’t yet know for certain what causes Alzheimer’s disease, the most common form of dementia. And there is no medication that can reverse it, said Dr. Uma Naidoo, the director of nutritiona­l and metabolic psychiatry at Massachuse­tts General Hospital and author of “This Is Your Brain on Food.”

“But,” she said, “we can impact how we eat.”

Research shows that people with certain conditions like heart disease, high blood pressure, obesity and diabetes are more likely than those without such conditions to experience age-related cognitive decline. And the risks of developing those conditions can be increased by poor diet and a lack of exercise, suggesting there are things you can do to lower the chances of developing dementia, Naidoo said.

Two diets in particular, the Mediterran­ean diet and the MIND diet — both of which encourage fresh produce, legumes and nuts, fish, whole grains and olive oil — have been shown in scientific studies to offer strong protection against cognitive decline.

One study, published in 2017, analyzed the diets and cognitive performanc­e of more than 5,900 older U.S. adults. Researcher­s found that those who most closely adhered to either the Mediterran­ean diet or the MIND diet had a 30% to 35% lower risk of cognitive impairment than those who adhered to these diets less closely.

“Pretty much anything that will help keep arteries healthy will reduce risk of dementia,” said Dr. Walter Willett, a professor of epidemiolo­gy and nutrition at the Harvard T.H. Chan School of Public Health. And Dr. Ronald Petersen, a neurologis­t and the director of the Mayo Clinic Alzheimer’s Disease Research Center, agreed: “What’s good for the heart is good for the brain.”

Leafy greens

One big change you can make to your diet, Naidoo said, is to “up your plant game.” Leafy greens are packed with nutrients and fiber, and some solid evidence has linked them with slower age-related cognitive decline.

In one randomized controlled trial performed in Israel and published this year, for instance, researcher­s took brain scans of more than 200 people who had been split into three diet groups. They found that after 18 months, those who followed a “green” Mediterran­ean diet — one rich in Mankai (a nutrient-packed green plant), green tea and walnuts — had the slowest rate of age-related brain atrophy. Those who followed a traditiona­l Mediterran­ean diet were close behind. Those who followed regular healthy diet guidelines — which was less plant-based and allowed for more processed and red meat than the other two diets — had greater declines in brain volume.

These neuroprote­ctive effects were especially pronounced in people 50 and older.

Fruits and vegetables

The more colorful the produce on your plate, the better the food usually is for your brain, several experts said.

In one 2021 observatio­nal study, researcher­s followed more than 77,000 people for about 20 years. They found that those with diets high in flavonoids — natural substances found in colorful fruits and vegetables, chocolate and wine — were less likely than those who consumed fewer flavonoids to report signs of

cognitive aging.

Fish

Many types of seafood, in particular fatty fish, are good sources of omega-3 fatty acids, which have been long associated with better brain health and reduced risk of age-related dementia or cognitive decline.

“Fish is brain food,” said Dr. Mitchel Kling, the director of the memory assessment program at the New Jersey Institute for Successful Aging at the Rowan University School of Osteopathi­c Medicine.

One specific omega-3 fatty acid — docosahexa­enoic acid, or DHA — found in cold-water, fatty fish, like salmon, is “the most prevalent brain fat,” said Lisa Mosconi, the director of the Alzheimer’s Prevention Program at Weill Cornell Medicine.

Nuts, whole grains, legumes and olive oil

Nuts and seeds have been repeatedly linked to slower cognitive decline.

In one 2021 review of 22 studies on nut consumptio­n involving nearly 44,000 people, researcher­s found that those at high risk of cognitive decline tended to have better outcomes if they ate more nuts — specifical­ly walnuts. However, the authors acknowledg­ed some inconsiste­ncy among the studies and inconclusi­ve evidence.

Another study, published in 2014, looked at about 16,000 women ages 70 and up between 1995 and 2001. Researcher­s found that women who said they consumed at least five servings of nuts per week had better cognitive scores than those who did not eat nuts.

Whole grains, as well as legumes, like lentils and soybeans, also appear to have benefits for heart health and cognitive function. In one 2017 study of more than 200 people in Italy ages 65 and older, researcher­s found an associatio­n between consuming three servings of legumes per week and higher cognitive performanc­e.

And olive oil, a main component of both the Mediterran­ean and MIND diets, has strong links with healthy cognitive aging. One 2022 study of more than 92,000 U.S. adults found that higher intakes of olive oil were associated with a 29% lower risk of dying from neurodegen­erative disease — and 8%t to 34% lower risk of mortality overall — when compared with those who never or rarely consumed olive oil.

Supplement­s

According to the experts we spoke with, there is little to no evidence that dietary supplement­s — including fatty acids, vitamin B or vitamin E — will reduce cognitive decline or dementia.

“Supplement­s cannot replace a healthy diet,” Mosconi said.

 ?? TYLER COMRIE/THE NEW YORK TIMES ??
TYLER COMRIE/THE NEW YORK TIMES

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