Tapering off meds is recommended

Dear Dr. Roach: I am a 61-year-old woman in fairly good health except that I have been taking prescription omeprazole once a day for heartburn for at least 10 years. I’ve read articles that say this isn’t good to take long term. When I’ve tried to stop by using famotidine instead, I still suffer from heartburn during the day. I’ve raised my bed and tried sleeping in an upright position. Your thoughts, please. — O.D.S.

It certainly is a good idea to periodically review with your doctor all the medications you take, to decide whether they are still necessary.

Proton pump inhibitors like omeprazole frequently are prescribed for short-term use but end up being continued for years.

Except in people who absolutely need it (such as people with Barrett’s esophagus), I agree with a trial of stopping and using H2 blockers like famotidine on an as-needed basis. I recommend a taper, not a sudden stop.

Proton pump inhibitors are likely to increase the risk of infection, such as pneumonia (without acid in the stomach, bacteria are not killed as efficiently) and intestinal infections; may possibly increase the risk of osteoporosis; and probably reduce vitamin B-12 and iron absorption.

Although there have been reports of increased risk of kidney disease and dementia, I doubt the actual clinical risk is significant. Still, there are enough possible adverse effects that it is worth balancing the risks against the benefits of reducing symptoms.

I am glad you tried some nondrug therapies. In addition to raising the head of the bed (bricks under the feet is traditional, but a foam wedge under the mattress is also effective), losing weight for those who would benefit, avoiding tobacco and alcohol, and not eating three hours before bedtime make drugs unnecessary for many.