Texarkana Gazette

Record count reported for paralyzing illness in U.S. children

- By Mike Stobbe The Associated Press Health & Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsibl­e for all content.

NEW YORK—This year has seen a record number of cases of a mysterious paralyzing illness in children, U.S. health officials said Monday.

It’s still not clear what’s causing the children to lose the ability to move their face, neck, back, arms or legs. The symptoms tend to occur about a week after the children had a fever and respirator­y illness.

No one has died from the rare disease this year, but it was blamed for one death last year and it may have caused others in the past.

What’s more, Centers for Disease Control and Prevention officials say many children have lasting paralysis. And close to half the kids diagnosed with it this year were admitted to hospital intensive care units and hooked up to machines to help them breathe.

The condition has been likened to polio, a dreaded paralyzing illness that once struck tens of thousands of U.S. children a year. Those outbreaks ended after a polio vaccine became available in the 1950s. Investigat­ors of the current outbreak have ruled out polio, finding no evidence of that virus in recent cases.

The current mystery can be traced to 2012, when three cases of limb weakness were seen in California. The first real wave of confirmed illnesses was seen in 2014, when 120 were reported. Another, larger wave occurred in 2016, when there were 149 confirmed cases. So far this year, there have been 158 confirmed cases.

In 2015 and 2017, the counts were far lower, and it’s not clear why.

The condition is called acute flaccid myelitis, or AFM. Investigat­ors have suspected it is caused by a virus called EV-D68. The 2014 wave coincided with a lot of EV-D68 infections and the virus “remains the leading hypothesis,” said Dr. Ruth Lynfield, a member of a 16-person AFM Task Force that the CDC establishe­d last month to offer advice to disease detectives.

But there is disagreeme­nt about how strong a suspect EV-D68 is. Waves of AFM and that virus haven’t coincided in other years, and testing is not finding the virus in every case. CDC officials have been increasing­ly cautious about saying the virus triggered the illnesses in this outbreak.

Indeed, EV-D68 infections are not new in kids, and many Americans carry antibodies against it.

Why would the virus suddenly be causing these paralyzing illnesses?

“This is a key question that has confounded us,” said the CDC’s Dr. Nancy Messonnier, who is overseeing the agency’s outbreak investigat­ion.

Experts also said it’s not clear why cases are surging in two-year cycles.

Another mystery: More than 17 countries have reported scattered AFM cases, but none have seen cyclical surges like the U.S. has.

When there has been a wave in the U.S., cases spiked in September and tailed off significan­tly by November. Last week, CDC officials said the problem had peaked, but they warned that the number of cases would go up as investigat­ors evaluated—and decided whether to count—illnesses that occurred earlier.

As of Monday, there were 311 illness reports still being evaluated.

This year’s confirmed cases are spread among 36 states. The states with the most are Texas, with 21, and Colorado, 15.

 ?? CDC via AP, File ?? ■ This 2014 file electron microscope image made available by the Centers for Disease Control and Prevention shows numerous spheroid-shaped Enteroviru­s-D68 virions. Doctors have suspected a mysterious paralyzing illness, acute flaccid myelitis, might be tied to the virus.
CDC via AP, File ■ This 2014 file electron microscope image made available by the Centers for Disease Control and Prevention shows numerous spheroid-shaped Enteroviru­s-D68 virions. Doctors have suspected a mysterious paralyzing illness, acute flaccid myelitis, might be tied to the virus.

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