Theory: Food allergies may be a factor in IBS
The New Mexican desert unrolled on either side of the highway like a canvas spangled at intervals by the smallest of towns. I was on a road trip with my 20-year-old son, Eli, from our home in Los Angeles to his college in Michigan. Eli, trying to be patient, plowed down Interstate 40 as daylight dimmed and I scrolled through my phone searching for a restaurant or dish that would not cause me pain. After years of carefully navigating dinners out and meals in, it had finally happened: There was nowhere I could eat.
“I’m so sorry, honey,” I said. “I feel really, really bad.” And I did. I was on the verge of tears, as much out of self-pity and shame as any maternal concern.
Eli shook his head. “It’s OK, Mom. It’s not your fault.”
My gut is not a carefree traveler. Ingest the wrong items, and my stomach feels as though someone’s scoured it with a Brillo pad. For the next few hours, I may also experience migraines, achy joints and a foggy, feverish sensation as though I’m coming down with the flu. My doctors call this irritable bowel syndrome, or IBS. I call it a terrible shame.
“Everybody has contractions in their gut,” said Dr. Emeran Mayer, a gastroenterologist at the University of California, Los Angeles, and the author of “The Mind-Gut Connection: How the Hidden Conversation Within Our Bodies Impacts Our Mood, Our Choices and Our Overall Health.”
The same contractions that go unnoticed by most people cause pain in IBS patients, who have become hypersensitive to sensations in their gut, he said. Calm the mind, the thinking goes, and the gut may follow.
Fair or not, I hear this prescription and think, “Oh, so this is all in my head?” Then I fear that my stomachaches are my fault, the product of an anxious mind that I cannot tame into submission.
My IBS journey started about nine years ago, at age 44, when I noticed that my migraines — for decades reliably yoked to my menstrual cycle — were accompanied by a sour stomach, like my gut was sucking on lemons. Cutting out gluten helped, but as the years passed, my gut continued to deteriorate.
Eventually I dropped 10 pounds because eating had become so painful. That’s why, in 2015, I landed in the office of a gastroenterologist. He ran a bunch of tests — blood, scopes — and when everything came back negative, he diagnosed me with IBS.
It could have started with a past infection, he said. Recent stresses in my life probably didn’t help. He had no way of curing me, but he advised me to relax more and manage my diet.
If my IBS was set off by stress, I thought, “I must be the most neurotic person I know.” Thoughts like these did not help me calm down. But that became my new goal: to relax so my belly would no longer hurt.
“It’s a very common thing in IBS patients,” he said. He added that an IBS patient’s system “looks at food as a potentially dangerous thing.”
Then, this August on that same trip with Eli, I read about a new theory for IBS. A paper published in The New England Journal of Medicine theorized that an abdominal infection could temporarily disturb the cell barrier that lines the colon. With the barrier disturbed, allergy-inducing proteins can get absorbed by the colon, setting off localized allergic reactions to certain inflammatory foods like gluten and leading to reverberations up and down the digestive tract.
I’d been telling people for years that I didn’t have allergies to certain foods, even though my body’s response to them felt automatic. Now this research seemed to indicate what I was feeling could be an allergic reaction — one that no amount of hypnotherapy or journaling was going to make disappear.
Later, I called Dr. Marc E. Rothenberg, one of the paper’s authors and the director of the division of allergy and immunology at Cincinnati Children’s Hospital Medical Center, to get more clarity.
“Stress modifies, and can exacerbate, the underlying disease physiology,” Rothenberg said. “But stress is not the cause of IBS.”
From time to time, I still try new remedies to improve digestion or better manage anxiety: a probiotic, Chinese herbs, a new meditation app. But if I’m never able to eat another grilled cheese sandwich (dairy cheese, wheat bread, actual butter), I can live with that. And that’s the most relaxing mantra there is.