The Atlanta Journal-Constitution

New study finds no evidence that pet cats cause schizophre­nia

Latest data should ease the fears of families with felines.

- By Washington Post

As if parents of young children didn’t have enough things to worry about, here’s another: Some scientists say they think pet cats might increase a kid’s risk of developing schizophre­nia.

But there’s good news out of this growing field of research, which focuses on the links between a cat-borne parasite that causes toxoplasmo­sis and mental health disorders. A new study of about 5,000 children in Britain found no evidence that cat ownership during gestation or childhood was associated with psychotic experience­s that can be early signs of mental illness — such as hallucinat­ions or delusions of being spied on — when they were teenagers.

The study, which was published in the journal Psychologi­cal Medicine, is the latest in a field that’s yielded many alarmist headlines based on correlatio­ns, but not concrete conclusion­s, about cats making people crazy. And it amounts to a big “not so fast.”

“Many people own cats, which are an important part of the life of many families,” co-author James Kirkbride, a psychiatri­c epidemiolo­gist at University College London, said in an email. “Our findings should reassure people that owning a cat in pregnancy or childhood is not related to later risk of psychotic symptoms.”

The cat-toxoplasmo­sis-psychosis nexus has gotten a lot of attention in recent years, but it’s hardly well understood.

It’s clear that the parasite that causes toxoplasmo­sis infections in people, T. gondii, depends entirely on cats, because it reproduces only in cat intestines and is spread via feline feces. And there’s “good evidence,” the study’s authors write, that T. gondii infections are associated with psychosis. So some researcher­s hypothesiz­e that owning cats in childhood increases the risk of developing mental illnesses, particular­ly schizophre­nia, and a handful of studies have supported this idea. But people can also become infected with T. gondii from undercooke­d meat or contaminat­ed water.

The new study is much larger than previous ones, and it’s based on data collected from children born in the early 1990s and tracked for decades as part of a longitudin­al birth cohort study in the area of Bristol, England. That meant the authors could feel certain whether a child grew up with a cat, whereas past research depended on adults recalling whether they had cats as kids — a method that “can often lead to results that are biased,” said co-author Francesca Solmi, also an epidemiolo­gist.

What the new research doesn’t answer is whether cat ownership during pregnancy and childhood is linked to later schizophre­nia, because the participan­ts haven’t yet reached the age of onset of that disorder, which typically develops between ages 18 and 25. But, Solmi added, that if there’s a cat-mental illness connection, the early signs would be detectable when the participan­ts were screened for psychotic experience­s at ages 13 and 18.

E. Fuller Torrey, a psychiatri­st and prominent researcher on the links between T. gondii and mental illness, cited that as one weakness of the study.

“The measuring of unusual experience­s and beliefs at age 13 is somewhat controvers­ial. I’ve raised two children, and both had unusual thinking at age 13,” said Torrey, who was one of the paper’s reviewers. “I think this will become much more important when they’re measuring who developed schizophre­nia out of this database.”

Torrey also noted that living with a kitty is not the only way cats might pass T. gondii to children.

“Even if we are suggesting that you get it at, say, age 4 when you’re playing in a sandbox, you don’t have to own a cat to have a cat go to the bathroom in it. The cat next door will go to the bathroom in it,” Torrey said, adding that he doesn’t think families with children should own cats. “I am not reassured by their findings that there’s no relationsh­ip.”

But, Solmi said, the findings indicate that owning a cat doesn’t amount to an additional risk for developing psychotic symptoms — in other words, if we assume T. gondii is a driver of mental health disorders, then having a cat around doesn’t seem to be more dangerous than other sources of infection, such as dirty vegetables. (Pregnant women should continue to avoid the litter box.)

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