The Atlanta Journal-Constitution

Future of virus testing uncertain

Arrival of vaccines has potential to decimate diagnostic­s demand.

- By Emma Court

It was a revealing moment for one of the biggest U.S. processors of coronaviru­s tests recently when Laboratory Corp of America Holdings Chief Executive Officer Adam Schechter said business in that service may decline by as much as half this year.

But later on the same conference call with analysts, Schechter all but reversed himself, acknowledg­ing that there could be “opportunit­y in the second half.”

“It’s just too hard to know right now,” he said.

The feeling is shared industry-wide. Companies like LabCorp saw their stocks surge as coronaviru­s testing became a key line of defense against the pathogen that’s killed almost half a million Americans. Yet vaccines have the potential to decimate demand for diagnostic­s, rendering a lot of

their scale-up superfluou­s.

LabCorp’s projection­s imply that coronaviru­s test- ing sales “are going to be essentiall­y zero in the sec- ond half of the year,” Nephron Research analyst Jack Meehan said to executives on the conference call.

As coronaviru­s vaccines become more widely accessible in the coming months, and more people gain protection from the coronaviru­s, testing needs are expected to ease. How quickly that happens and by how much, though, is uncertain, with the pace of immunizati­on, the durability of shots and the emergence of more contagious variants all unknown factors.

Meanwhile, some industry observers are still pushing for expansion. Screen- ings will be key as long as vaccines aren’t widely available, according to Michael Mina, a Harvard epidemiolo­gist. Low-cost, easy to manufactur­e tests made by companies like Innova Medical Group Inc. can also play a lasting role at the entrances of workplaces, shopping centers and restaurant­s, he said.

Mina wants the federal government to invest $20 billion this year in ramping up testing supply. He says $5 billion to $10 billion could put tests in every home, allowing people to be screened two to three times a week for six months.

“Testing’s not going anywhere,” he said.

But for laboratori­es and testing manufactur­ers that spent the last year scrambling to meet insatiable test- ing demand, forecastin­g has become a maze. LabCorp expects non-COVID-19 testing to rebound as higher-margin virus testing recedes.

“It’s going to be important for them to make sure they’re prepared for what- ever’s next,” said Lisa Gill, managing director and senior equity analyst at JPMorgan Chase & Co.

The threshold for herd immunity, when an entire community is protected though not everyone has been immunized, has been estimated as coming when about 70% to 85% of the 330 million Americans have received shots or been exposed to COVID-19, experts say.

“That’s when you’ll really see utilizatio­n start to fall,” said William Morice, president of Mayo Clinic Laboratori­es, who described the demand for coronaviru­s testing to date as something he had never seen before in his career. “If it doesn’t, that’s not a good sign.”

Growing recognitio­n that coronaviru­s testing sales won’t last forever has shadowed companies’ share growth, despite standout financial results, said Richard Newitter, managing director and senior equity research analyst at SVB Leerink. The iShares U.S. Medical Devices ETF, which holds shares of test manufactur- ers like Abbott Laborato- ries, Thermo Fisher Scien- tific Inc. and Becton Dickin- son and Co., has risen nearly 26% over the last year.

Quest Diagnostic­s Inc., another major U.S. labo- ratory, said Tuesday that demand for COVID-19 diag- nostic testing has fallen, and most results are returned in a day, “faster than at any other time during the pandemic.” There could still be another surge in cases, the company said, and it is still adding more coronaviru­s testing capacity.

Still, there is growing agreement that even in the best of circumstan­ces, coronaviru­s tests will play a long- term role in control efforts. Flu tests, for example, are still common despite the widespread use of vaccines.

Coronaviru­s tests are likely to become part of panels that will be used to screen anyone with telltale symptoms, according to JPMorgan’s Gill. LabCorp does 130,000 to 135,000 tests daily, and Gill said those numbers could fall by 90% to 95% beyond 2021. LabCorp says it has capacity to process 275,000 coronaviru­s tests a day.

That world might also include testing available in new places, including when people do higher-risk activities.

“We do believe we’ll start to see more of a nontraditi­onal use of these tests” in places like airports and on cruise lines, said Dave Hickey, executive vice president and president of life sciences at Becton Dickinson, due to “the ability of these tests to sort of open up the economy.”

Becton Dickinson is in the “very early days” of looking at these types of new opportunit­ies, Hickey said.

The U.S. government, meanwhile, made investment­s as recently as early this month in expanding the supply of tests that can be performed by consumers at home or by healthcare workers in medical settings. Such manufactur­ing can take many months to years to scale up.

 ?? PATRICK T. FALLON / BLOOMBERG ?? COVID-19 testing is expected to still have a demand for a while, but how much will be needed is difficult to predict.
PATRICK T. FALLON / BLOOMBERG COVID-19 testing is expected to still have a demand for a while, but how much will be needed is difficult to predict.

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